Using neuroimaging to predict treatment response in mood and anxiety disorders

Annals of Clinical Psychiatry : Official Journal of the American Academy of Clinical Psychiatrists
Karleyton C EvansScott L Rauch

Abstract

Functional neuroimaging has begun to show promise as a clinical tool in the prediction of treatment response in mood and anxiety disorders. Given the variance in patient responses to psychiatric treatments, the use of such predictive tools could be tremendously valuable, especially in situations where treatments carry substantial risks or costs. A literature search was conducted in December 2004 to identify published neuroimaging treatment prediction papers. "Neuroimaging," "treatment," and "depression or anxiety" were used as keywords. Studies of treatment prediction were complemented by studies of treatment effects to provide context. Fifteen original published papers were identified as investigations of treatment prediction in mood and anxiety disorders. These studies have predominantly been conducted in patients with major depression (MDD) and obsessive-compulsive disorder (OCD). We review this literature and provide a discussion of design considerations in psychiatric neuroimaging studies of treatment response prediction. The neuroimaging literature pertaining to treatment response prediction is largely limited to studies of MDD and OCD. While these initial reports are preliminary, the findings reviewed suggest that treatm...Continue Reading

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Citations

Jun 10, 2008·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Karleyton C EvansScott L Rauch
May 24, 2012·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Vanda FariaTomas Furmark
Apr 24, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Clinton B McCracken, Anthony A Grace
Jan 26, 2010·Revista brasileira de psiquiatria : orgão oficial da Associação Brasileira de Psiquiatria, Asociación Psiquiátrica de la América Latina·Marcelo Queiroz HoexterEuripedes Constantino Miguel
Sep 19, 2014·European Archives of Psychiatry and Clinical Neuroscience·Wolfgang Retz, Petra Retz-Junginger
Dec 16, 2016·Journal of Clinical Psychopharmacology·Wei QiArieh Shalev
Nov 26, 2010·Journal of Psychopharmacology·Hamid AlhajR Hamish McAllister-Williams
Sep 17, 2008·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Günter SchiepekOliver Pogarell
Mar 27, 2018·Depression and Anxiety·F C W van KrugtenUNKNOWN Decision Tool Unipolar Depression Consortium
Jan 1, 2011·Personalized Medicine·Torsten Klengel, Elisabeth B Binder

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