PMID: 11909061Mar 23, 2002Paper

Using patterned substrates to promote mixing in microchannels

Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics
Olga KuksenokAnna C Balazs

Abstract

Using a lattice Boltzmann model for fluid dynamics, we investigate the flow and phase behavior of a binary fluid moving over a patterned substrate within a microchannel. The binary fluid consists of two immiscible components, A and B, and this liquid is subjected to a Poiseuille flow. The substrate is decorated with a checkerboard pattern of A- and B-like patches. Through a coupling of hydrodynamics and thermodynamics, each component is driven to flow from the nonwettable domains to wettable regions. As a consequence, the A and B fluids undergo extensive mixing within the microchannels. We investigate how the degree of mixing depends on the size of the patches, the velocity of the imposed flow field, and the characteristics of the fluid. The results provide guidelines for creating localized "mixing stations" within microfluidic devices. The findings also reveal how a combination of imposed flow fields and surface patterning can be exploited to control the phase behavior of complex fluids.

References

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Citations

Sep 16, 2005·The Journal of Chemical Physics·Rui D M TravassoAnna C Balazs
Jan 26, 2007·The Journal of Chemical Physics·J A Thomas, A J H McGaughey
Dec 25, 2008·Lab on a Chip·Kazunori IidaMichael J Fasolka
Apr 14, 2016·Integrative Biology : Quantitative Biosciences From Nano to Macro·Joseph O'ConnorAlistair Revell
Apr 25, 2012·Electrophoresis·Cunlu Zhao, Chun Yang
Mar 4, 2009·Lab on a Chip·Lingling ShuiJan C T Eijkel
Aug 17, 2020·Physical Review. E·Prasenjit DasSanjay Puri
Jul 7, 2011·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Chanil JeonYoungkyun Jung
Nov 13, 2009·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Srikanth DhondiShaun C Hendy
Oct 21, 2020·Physical Review. E·Prasenjit DasSanjay Puri
Dec 20, 2003·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Olga KuksenokAnna C Balazs
Dec 31, 2005·Physical Review Letters·Olga KuksenokAnna C Balazs
Aug 11, 2005·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·S C HendyJ Burnell
Sep 4, 2008·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Taehun Lee, Lin Liu
Aug 26, 2003·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Olga Kuksenok, Anna C Balazs
Jun 29, 2006·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Michael M DupinChris M Care
Nov 7, 2019·Langmuir : the ACS Journal of Surfaces and Colloids·Sergey A Vagner, Stanislav A Patlazhan
Feb 7, 2007·Analytical Chemistry·Zheng XiaZ Hugh Fan

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