Abstract
Mice provide an unlimited source of animal models to study mammalian gene function and human diseases. The powerful genetic modification toolbox existing for the mouse genome enables the creation of, literally, thousands of genetically modified mouse strains, carrying spontaneous or induced mutations, transgenes or knock-out/knock-in alleles which, in addition, can exist in hundreds of different genetic backgrounds. Such an immense diversity of individuals needs to be adequately annotated, to ensure that the most relevant information is kept associated with the name of each mouse line, and hence, the scientific community can correctly interpret and benefit from the reported animal model. Therefore, rules and guidelines for correctly naming genes, alleles and mouse strains are required. The Mouse Genome Informatics Database is the authoritative source of official names for mouse genes, alleles, and strains. Nomenclature follows the rules and guidelines established by the International Committee on Standardized Genetic Nomenclature for Mice. Herewith, both from the International Society for Transgenic Technologies (ISTT) and from the scientific journal Transgenic Research, we would like to encourage all our colleagues to adhere a...Continue Reading
References
Sep 30, 1994·Gene·M T Davisson
Oct 10, 1997·Transgenic Research·M T Davisson
Oct 15, 1997·Genomics·L J MaltaisM T Davisson
Apr 12, 2002·Genomics·Lois J MaltaisIan Jackson
Nov 19, 2003·The European Journal of Neuroscience·Francina LangaLluís Montoliu
Nov 25, 2003·Circulation Research·Sébastien AlcoléaHarold van Rijen
Jul 15, 2004·Pigment Cell Research·Estela GiménezLluís Montoliu
Sep 2, 2004·Nature Genetics·Johan AuwerxWolfgang Wurst
Mar 22, 2005·European Journal of Pharmacology·Cruz Miguel CendánJosé M Baeyens
Feb 1, 2006·Journal of Neurochemistry·Alfonso LavadoLluís Montoliu
Oct 31, 2007·Briefings in Functional Genomics & Proteomics·Roland H FriedelWolfgang Wurst
Feb 22, 2008·Transgenic Research·Hua TangKenichi Yamamura
Jun 25, 2008·Transgenic Research·Asuka IwanagaKatsuji Yoshioka
Jun 16, 2009·Nature Methods·Stephen J PettittWilliam C Skarnes
Jul 9, 2009·Transgenic Research·Jean-Louis MichaudChris R J Kennedy
Sep 29, 2009·Nucleic Acids Research·Phil WilkinsonDamian Smedley
Citations
Feb 4, 2012·Transgenic Research·Michael StaudtJohannes Schenkel
Feb 26, 2013·Transgenic Research·I A BurkovO L Serov
Oct 20, 2012·Gastroenterology·Malcolm J Low
Nov 1, 2016·Journal of Neurochemistry·Steven W Barger
Feb 16, 2017·Annual Review of Animal Biosciences·Stacey J Sukoff Rizzo, Jacqueline N Crawley
Dec 22, 2017·Transgenic Research·Alexander V SmirnovOleg L Serov
Mar 21, 2019·Animal Models and Experimental Medicine·Qi Kong, Chuan Qin
Jul 15, 2020·PLoS Biology·Nathalie Percie du SertHanno Würbel
Sep 25, 2020·Scientific Reports·Davide SeruggiaLluis Montoliu
Sep 19, 2021·Mammalian Genome : Official Journal of the International Mammalian Genome Society·M-C BirlingL Teboul