Using the age-adjusted Charlson comorbidity index to predict outcomes in emergency general surgery

The Journal of Trauma and Acute Care Surgery
Etienne St-LouisKosar Khwaja

Abstract

We evaluated the role of the Charlson age-comorbidity index (CACI), a weighted comorbidity index that reflects cumulative increased likelihood of 1-year mortality, in predicting perioperative outcomes in an emergency general surgery population at a large Canadian teaching hospital. A retrospective chart review of emergency general surgery admissions in 2010 was conducted. Patients who had surgery were identified. Mode of surgery and CACI were recorded, as well as measures of outcome, including 30-day mortality and intensive care unit (ICU) admission. A multivariate stepwise logistic regression model was created to assess the effect of age-adjusted Charlson comorbidity index on postoperative outcomes while controlling for the effect of possible confounders. The prediction ability of CACI for mortality was assessed using receiver operating characteristic analyses considering the area under the curve and its 95% confidence intervals (CIs). Of the 529 admissions to general surgery from the emergency department, 257 patients underwent a surgical intervention. The CACI scores ranged from 0 to 16. We described a total of 11 deaths (4.3%) and 30 ICU admissions (11.7%). CACI was associated with an increased risk of 30-day mortality (adj...Continue Reading

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Citations

Dec 2, 2015·The British Journal of Surgery·K F DesserudK Søreide
Jul 25, 2015·ANZ Journal of Surgery·Anton M MusiienkoAnita R Skandarajah
Aug 25, 2016·The Journal of Arthroplasty·William K OelsnerJonathan G Schoenecker
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Jun 4, 2015·European Journal of Trauma and Emergency Surgery : Official Publication of the European Trauma Society·E St-LouisK Khwaja
Jan 25, 2020·The Journal of Trauma and Acute Care Surgery·Morgan E SindallAndrew C Bernard
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Jan 25, 2020·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·Davide Zattoni, Dimitri Christoforidis
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