Usnic acid-loaded polyaniline/polyurethane foam wound dressing: preparation and bactericidal activity

Materials Science & Engineering. C, Materials for Biological Applications
Marcelo R Dos SantosHelinando P de Oliveira

Abstract

The improved bactericidal activity of new composites for wound dressing prototypes represents an important strategy for development of more efficient devices that make use of synergistic interaction between components. The doping level of polyaniline represents a critical parameter for its corresponding biologic activity. In this work, it is explored the doping effect of usnic acid on undoped polyaniline, that introduces important advantages namely, improved bactericidal activity of polyaniline and the anti-biofilm properties of lichen derivative. The deposition of the resulting material on polyurethane foam potentializes its applicability as wound dressing, characterizing a new platform for application against Escherichia coli and Staphylococcus aureus.

Citations

Jun 14, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Alexandra Elena StoicaAlexandru Mihai Grumezescu
Apr 9, 2020·Frontiers in Bioengineering and Biotechnology·Chenyu ShiJincheng Wang
Dec 29, 2020·Macromolecular Bioscience·Xiaoying ZhaQifeng Jiang
Feb 1, 2020·International Journal of Biological Macromolecules·Asghar EskandariniaHossein Salehi
Sep 11, 2019·Journal of Medicinal Chemistry·Ehsan Nazarzadeh ZareGiuseppe Perale

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