PMID: 19942805Nov 28, 2009Paper

Uterine adenocarcinoma with prominent desmoplasia in a geriatric miniature pig

The Journal of Veterinary Medical Science
Hossain GolbarJyoji Yamate

Abstract

A 10-year-old miniature sow was died, showing inappetence and weight loss. Grossly, neoplastic enlargement of the uterus was found. Histopathologically, the lesions consisted of acinar, ductular and cystic proliferations of mono- and multilayered epithelial cells; these cells reacted immunohistochemically strongly with three different cytokeratin antibodies, and occasionally to vimentin. Myofibroblastic desmoplastic cells, positive to alpha-smooth muscle actin, were present among neoplastic cells. Metastatic lesions were seen in the lungs and liver. Based on these findings, a diagnosis of uterine adenocarcinoma with marked desmoplasia was made. This case is the second report of uterine adenocarcinoma in the miniature pig.

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Citations

Nov 5, 2015·Tierärztliche Praxis. Ausgabe K, Kleintiere/Heimtiere·D HöltigA von Altrock

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