Uterine angiomyolipoma: case report and review of the literature

Pathology International
H YaegashiH Sasano


Extrarenal angiomyolipomas (AML) have been reported at various anatomical sites, but infrequently in the gynecological region. In the uterus, only a few cases have been described. We describe a uterine angiomyolipoma occurring in a 40-year-old woman without evidence of tuberous sclerosis. The tumor arose on the right wall of the uterine body and was partially cystic, and it was associated with marked degeneration. It was composed of mature adipose tissue, anomalous blood vessels and non-vascular smooth muscle cells. Immunohistochemistry revealed that non- vascular smooth muscle cells were positive for alpha-smooth muscle actin (alpha-SMA), desmin, vimentin, antihuman muscle actin (HHF35) and progesterone receptor (PR), and negative for cytokeratin, antihuman melanoma (HMB45), CD34, S-100 and estrogen receptor (ER). It is of particular interest that non-vascular smooth muscle cells were negative for HMB45, in contrast to renal and other extrarenal AML in which HMB45 immunoreactivity has been demonstrated in these cells.


Jan 1, 1989·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·W Sieiński
Dec 1, 1988·The Journal of Laryngology and Otology·E E DawlatlyA Y el-Hassan
Sep 1, 1973·American Journal of Clinical Pathology·R I DemopoulosV Kaji
Mar 1, 1982·The Journal of Urology·J Friis, A Hjortrup
Jan 1, 1995·American Journal of Obstetrics and Gynecology·M S ReinA J Friedman
Nov 1, 1994·The American Journal of Surgical Pathology·M ShimizuT Hata
Jul 1, 1993·American Journal of Obstetrics and Gynecology·D D BrandonG M Clinton
Sep 1, 1993·Gynecologic Oncology·F LaffargueA Lachard
Aug 1, 1996·Journal of Cutaneous Pathology·J F Val-Bernal, C Mira
Jan 15, 1999·The American Journal of Surgical Pathology·W M TsuiA P Dhillon
Jan 19, 1999·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Y L ZhaiS Fujii
Sep 9, 1999·The American Journal of Surgical Pathology·H L'HostisJ M Coindre
Jan 19, 2000·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·P B Clement
Jul 1, 1965·American Journal of Clinical Pathology·D S JACOBSJ S JOHNSON

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