Uterine angiomyolipoma: case report and review of the literature

Pathology International
H YaegashiH Sasano

Abstract

Extrarenal angiomyolipomas (AML) have been reported at various anatomical sites, but infrequently in the gynecological region. In the uterus, only a few cases have been described. We describe a uterine angiomyolipoma occurring in a 40-year-old woman without evidence of tuberous sclerosis. The tumor arose on the right wall of the uterine body and was partially cystic, and it was associated with marked degeneration. It was composed of mature adipose tissue, anomalous blood vessels and non-vascular smooth muscle cells. Immunohistochemistry revealed that non- vascular smooth muscle cells were positive for alpha-smooth muscle actin (alpha-SMA), desmin, vimentin, antihuman muscle actin (HHF35) and progesterone receptor (PR), and negative for cytokeratin, antihuman melanoma (HMB45), CD34, S-100 and estrogen receptor (ER). It is of particular interest that non-vascular smooth muscle cells were negative for HMB45, in contrast to renal and other extrarenal AML in which HMB45 immunoreactivity has been demonstrated in these cells.

References

Jan 1, 1989·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·W Sieiński
Dec 1, 1988·The Journal of Laryngology and Otology·E E DawlatlyA Y el-Hassan
Sep 1, 1973·American Journal of Clinical Pathology·R I DemopoulosV Kaji
Mar 1, 1982·The Journal of Urology·J Friis, A Hjortrup
Jan 1, 1995·American Journal of Obstetrics and Gynecology·M S ReinA J Friedman
Nov 1, 1994·The American Journal of Surgical Pathology·M ShimizuT Hata
Jul 1, 1993·American Journal of Obstetrics and Gynecology·D D BrandonG M Clinton
Sep 1, 1993·Gynecologic Oncology·F LaffargueA Lachard
Aug 1, 1996·Journal of Cutaneous Pathology·J F Val-Bernal, C Mira
Jan 15, 1999·The American Journal of Surgical Pathology·W M TsuiA P Dhillon
Jan 19, 1999·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Y L ZhaiS Fujii
Sep 9, 1999·The American Journal of Surgical Pathology·H L'HostisJ M Coindre
Jan 19, 2000·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·P B Clement
Jul 1, 1965·American Journal of Clinical Pathology·D S JACOBSJ S JOHNSON

❮ Previous
Next ❯

Citations

Oct 16, 2004·Pathology International·Thida AungSuguru Yonezawa
Mar 8, 2008·International Seminars in Surgical Oncology : ISSO·Oluwole Fadare
Jul 25, 2007·AJR. American Journal of Roentgenology·Kazuhiro KitajimaKazuro Sugimura
Apr 19, 2003·Journal of Computer Assisted Tomography·Toshiya MaebayashiTakao Mochizuki
Jan 25, 2005·Journal of Computer Assisted Tomography·Khaled M ElsayesJeffrey J Brown
Feb 13, 2016·Molecular and Clinical Oncology·Guang-Xiang ChenFu-Gang Han
Feb 12, 2021·Archives of Gynecology and Obstetrics·Jiao WangDandan Wang
Jan 23, 2004·Archives of Pathology & Laboratory Medicine·Ru-Long Ren, Howard Her-Juing Wu

❮ Previous
Next ❯

Related Concepts

Related Feeds

Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is a clinically and genetically heterogeneous disease with approximately 20,000 cases per year in the United States. AML also accounts for 15-20% of all childhood acute leukemias, while it is responsible for more than half of the leukemic deaths in these patients. Here is the latest research on this disease.

AML: Role of LSD1 by CRISPR (Keystone)

Find the latest rersearrch on the ability of CRISPR-Cas9 mutagenesis to profile the interactions between lysine-specific histone demethylase 1 (LSD1) and chemical inhibitors in the context of acute myeloid leukemia (AML) here.

Related Papers

The Laryngoscope
A R CLIMIEK L KRABBENHOFT
Cytopathology : Official Journal of the British Society for Clinical Cytology
T Stoos-VeicG Aralica
Journal of Clinical Ultrasound : JCU
Heidi L BraunJohn W Seeds
© 2021 Meta ULC. All rights reserved