Uterine involution and fertility of holstein cows subsequent to early postpartum PGF2alpha treatment for acute puerperal metritis

Journal of Dairy Science
P MelendezG A Donovan

Abstract

The objective was to evaluate the effect of 2 doses of PGF(2alpha) injected early postpartum on uterine involution, serum concentration of acute phase proteins at 12 d postpartum, and fertility in Holstein cows with acute puerperal metritis. Only cows diagnosed with retained fetal membranes and metritis and treated with ceftiofur hydrochloride for 5 d were used in the study. Two hundred cows were assigned randomly to be treated (n = 100) or to serve as controls (n = 100). Treatment consisted of 2 i.m. injections of PGF(2alpha) 8 h apart on d 8 postpartum. A subsample of 90 cows was selected randomly (45 treated cows; 45 controls) to evaluate uterine diameter using ultrasonography, uterine score, and serum concentrations of acute phase proteins at 12 d postpartum. The outcome variable for all cows was conception rate at first service. Postpartum, primiparous, treated cows had smaller uterine diameters and lower uterine scores than controls. Cows with a uterine diameter <5.1 cm at 12 d postpartum were 5.5 times more likely to conceive at first service than cows with larger uterine horn diameter. Treatment significantly reduced the concentrations of serum alpha1-acid glycoprotein. Within primiparous cows, treatment also increased ...Continue Reading

References

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Citations

Jul 23, 2014·Asian-Australasian Journal of Animal Sciences·K H LeeC H Chi
Jun 22, 2007·Journal of Dairy Science·J M HuzzeyM A G von Keyserlingk
Jan 24, 2009·Journal of Dairy Science·J M HuzzeyM A G von Keyserlingk
Feb 20, 2008·Reproduction in Domestic Animals = Zuchthygiene·C VanderhaegheD Maes
Jan 16, 2009·Reproduction in Domestic Animals = Zuchthygiene·S O JuchemJ E P Santos
May 15, 2020·Reproduction in Domestic Animals = Zuchthygiene·Scott E PoockMatthew C Lucy
Jun 29, 2015·Journal of Dairy Science·A MahnaniV E Cabrera
Jun 16, 2005·The Veterinary Clinics of North America. Food Animal Practice·Grant S Frazer
Feb 19, 2008·Animal Reproduction Science·O I Azawi

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