Uterine papillary serous carcinoma: study of 19 cases

European Journal of Obstetrics, Gynecology, and Reproductive Biology
B PiuraR Dgani

Abstract

Uterine papillary serous carcinoma (UPSC) is an uncommon highly malignant variant of endometrial carcinoma that histologically and clinically resembles ovarian papillary serous carcinoma. The purpose of this study was to present the conjoined experience of two regional hospitals in the south of Israel (Soroka Medical Center, Beer-Sheva and Kaplan Hospital, Rehovot) of handling this tumour. Data from the files of 19 patients with UPSC who were managed at these hospitals between July 1991 and June 1997 were evaluated. The three-year survival rate was 57.3% overall; 83.3% for Stage I and 21.2% for Stages II, III, and IV combined (P<0.02). Eighteen patients had primary surgery which included total abdominal hysterectomy and bilateral salpingo-oophorectomy and 15 (83.3%) of them received postoperative adjuvant therapy which included radiotherapy and/or systemic chemotherapy. The prognosis of patients with UPSC is worse than that of patients with other forms of endometrial carcinoma. Primary surgery comprised of total abdominal hysterectomy, bilateral salpingo-oophorectomy and staging is the mainstay of treatment. The type of postoperative treatment is not consistent. By and large, adjuvant pelvic radiotherapy is usually given in ear...Continue Reading

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Citations

Dec 17, 2003·Gynecologic Oncology·Brian M SlomovitzKaren H Lu
Jan 31, 2004·Gynecologic Oncology·L ElitM Carey
Aug 12, 2003·International Journal of Radiation Oncology, Biology, Physics·Brij M SoodB Vikram
Oct 25, 2003·International Journal of Radiation Oncology, Biology, Physics·Neil MehtaArno J Mundt
Mar 10, 2001·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·E. H. Tay, B. G. Ward
Jun 8, 2000·The American Journal of Surgical Pathology·D T WheelerM E Sherman
Sep 16, 2011·ISRN Obstetrics and Gynecology·Laurie ElitWaldo Jimenez
Oct 6, 2000·International Journal of Radiation Oncology, Biology, Physics·R S SmithN N Teng
Oct 4, 2005·International Journal of Radiation Oncology, Biology, Physics·Chad A HamiltonJohn K Chan
Sep 9, 2008·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Emma C BatchelorJoseph M Jenrette
Jul 28, 2004·International Journal of Radiation Oncology, Biology, Physics·Janice KwonEdmee Franssen
May 3, 2006·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·T Biron-ShentalA Fishman
Oct 3, 1999·Current Opinion in Oncology·R E Bristow
Dec 21, 2010·Expert Review of Anticancer Therapy·Thijs RoelofsenLeon F Massuger

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