Uterus transplantation in women who are genetically XY

Journal of Medical Ethics
Amani SampsonGwendolyn P Quinn

Abstract

Uterus transplantation is an emerging technology adding to the arsenal of treatments for infertility; specifically the only available treatment for uterine factor infertility. Ethical investigations concerning risks to uteri donors and transplant recipients have been discussed in the literature. However, missing from the discourse is the potential of uterus transplantation in other groups of genetically XY women who experience uterine factor infertility. There have been philosophical inquiries concerning uterus transplantation in genetically XY women, which includes transgender women and women with complete androgen insufficiency syndrome. We discuss the potential medical steps necessary and associated risks for uterus transplantation in genetically XY women. Presently, the medical technology does not exist to make uterus transplantation a safe and effective option for genetically XY women, however this group should not be summarily excluded from participation in trials. Laboratory research is needed to better understand and reduce medical risk and widen the field to all women who face uterine factor infertility.

References

Feb 24, 2012·Transplant International : Official Journal of the European Society for Organ Transplantation·Ariel LefkowitzJacques Balayla
Jun 16, 2012·Lancet·Ieuan A HughesJane MacDougall
Aug 24, 2016·European Journal of Obstetrics, Gynecology, and Reproductive Biology·S HuetT Gauthier
Aug 29, 2017·Revista brasileira de ginecologia e obstetrícia : revista da Federação Brasileira das Sociedades de Ginecologia e Obstetrícia·Théo LernerEdmund Chada Baracat
Feb 3, 2018·Journal of Gynecology Obstetrics and Human Reproduction·T GauthierUNKNOWN Comité d’étude de la Transplantation Utérine en France (CETUF) du CNGOF
Mar 27, 2018·Journal of Gynecology Obstetrics and Human Reproduction·A Favre-InhoferJ M Ayoubi
Jun 6, 2018·BJOG : an International Journal of Obstetrics and Gynaecology·I KisuD Aoki
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Citations

Oct 13, 2021·Current Opinion in Organ Transplantation·Briget da GracaAnji Wall

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