Utilities for asthma and COPD according to category of severity: a comprehensive literature review

Journal of Medical Economics
Thomas R EinarsonMichiel E H Hemels

Abstract

Asthma and chronic obstructive pulmonary disease (COPD) are incurable diseases that impact quality-of-life. To summarize original research articles that measured or utilized preference-based utilities or disutilities according to disease severity. Medline and Embase were searched from inception until the end of November 2014. Two reviewers independently searched the literature with differences settled through discussion. Data extracted included utility scores as determined in original research categorized according to disease severity as well as disutilities associated with exacerbations or comorbidities. Data were tabulated and analyzed descriptively. In total, 862 articles were identified, 790 were rejected, and 69 analyzed. There were 44 dealing with COPD and 25 with asthma. Average utilities determined by research were 0.828 ± 0.062, 0.765 ± 0.090, 0.711 ± 0.120, and 0.607 ± 0.120 for mild, moderate, severe, and very severe COPD, respectively. Utilities used in economic analyses were 0.866 ± 0.038, 0.770 ± 0.024, 0.739 ± 0.045, and 0.596 ± 0.075, respectively. Disutilities (annual) ranged from 0.002-0.378; major and minor exacerbations had respective disutilities of 0.287 and 0.108. For asthma patients, utilities were for 0...Continue Reading

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Citations

Jun 22, 2016·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Foruhar MoayeriDavid Dunt
Jun 19, 2021·Expert Review of Pharmacoeconomics & Outcomes Research·Buendía Jefferson AntonioMelisa Lopez Moreno
Sep 3, 2021·Pediatric Pulmonology·Jefferson Antonio BuendíaHernan Lucio Talamoni
Sep 14, 2021·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Jefferson Antonio BuendíaJohn Edwin Feliciano-Alfonso
Sep 24, 2021·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Jefferson Antonio BuendiaYamith Eutimio Cossio-Giraldo
Dec 4, 2021·Expert Review of Pharmacoeconomics & Outcomes Research·Jefferson Antonio Buendía, Diana Guerrero Patiño
Dec 7, 2021·BMC Pulmonary Medicine·Jefferson Antonio Buendía, Diana Guerrero Patiño
Dec 7, 2021·BMC Pulmonary Medicine·Jefferson Antonio Buendía, Diana Guerrero Patiño
Dec 17, 2021·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Jefferson Antonio Buendía, Diana Guerrero Patiño

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