Utility of amylase and lipase as predictors of grade of injury or outcomes in pediatric patients with pancreatic trauma

Journal of Pediatric Surgery
Richard HermanPeter F Ehlrich

Abstract

Grade of injury, serum amylase, and lipase are markers used to assess pancreatic injury. It is unclear how amylase and lipase relate to grade of injury or predict outcome. We hypothesize that serum amylase and lipase are good predictors of grade of injury and outcomes in patients with pancreatic trauma. This study is a multicenter review from 9 pediatric trauma centers of all children admitted to their institution over 5 years with a pancreatic injury. Initial as well as peak amylase and lipase values were analyzed with relation to pancreatic grade, length of stay, and outcomes. One hundred thirty-one records were analyzed. There were 44 girls and 85 boys with an average age of 9.0 ± 0.4 years. The mean injury severity score (ISS) score was 15.5 ± 1.2 SE. The average length of stay (in days) was analyzed by grades 0 (3.93), 1 (7.73), 2 (13.4), 3 (18.4), 4 (31), and 5 (13.5). Neither initial nor peak amylase/lipase correlated with grade of injury. Neither amylase nor lipase predicted length of stay or mortality. Maximal amylase was highly predictive of developing a pseudocyst. There seems to be limited value for repetitive routine amylase and lipase levels in the management of pediatric trauma patients with pancreatic injury.

References

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Citations

Nov 28, 2013·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·Kun-Lin XieHong Wu
Jun 1, 2014·European Journal of Trauma and Emergency Surgery : Official Publication of the European Trauma Society·B MitraC Atkin
Feb 10, 2016·Pediatric Surgery International·Bahattin AydogduSelcuk Otcu
Jan 15, 2016·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·Calogero IaconoAlfredo Guglielmi
May 17, 2013·World Journal of Gastrointestinal Endoscopy·Paola De AngelisLuigi Dall'oglio
Dec 2, 2017·ANZ Journal of Surgery·Tishanthan PathmarajahDieter G Weber
Mar 17, 2016·World Journal of Radiology·Atin KumarShivanand Gamanagatti
Apr 27, 2018·Pediatric Emergency Care·Matthew CullyM Olivia Titus
Jan 6, 2018·Pediatric Gastroenterology, Hepatology & Nutrition·Ravi Kumar Garg, Jai Kumar Mahajan
Dec 20, 2015·The Journal of Trauma and Acute Care Surgery·Sara C FallonBindi J Naik-Mathuria
Nov 15, 2018·Pediatric Surgery International·Adam M VogelChristian J Streck
Dec 24, 2019·World Journal of Emergency Surgery : WJES·Federico CoccoliniUNKNOWN WSES-AAST Expert Panel
Sep 21, 2017·The Journal of Trauma and Acute Care Surgery·Bindi J Naik-MathuriaUNKNOWN the Pancreatic Trauma Study Group (PTSG) Collaborators:
Dec 6, 2014·Journal of Surgical Case Reports·Adarsh VijayHassan Al-Thani
Dec 7, 2020·Journal of Hepato-biliary-pancreatic Sciences·Yasuhisa AndoYasuyuki Suzuki
May 7, 2020·Hormone Molecular Biology and Clinical Investigation·Seyed Mohammad HosseininejadMohammad Tabarestani

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