Utility of amylase and lipase as predictors of grade of injury or outcomes in pediatric patients with pancreatic trauma

Journal of Pediatric Surgery
Richard HermanPeter F Ehlrich


Grade of injury, serum amylase, and lipase are markers used to assess pancreatic injury. It is unclear how amylase and lipase relate to grade of injury or predict outcome. We hypothesize that serum amylase and lipase are good predictors of grade of injury and outcomes in patients with pancreatic trauma. This study is a multicenter review from 9 pediatric trauma centers of all children admitted to their institution over 5 years with a pancreatic injury. Initial as well as peak amylase and lipase values were analyzed with relation to pancreatic grade, length of stay, and outcomes. One hundred thirty-one records were analyzed. There were 44 girls and 85 boys with an average age of 9.0 ± 0.4 years. The mean injury severity score (ISS) score was 15.5 ± 1.2 SE. The average length of stay (in days) was analyzed by grades 0 (3.93), 1 (7.73), 2 (13.4), 3 (18.4), 4 (31), and 5 (13.5). Neither initial nor peak amylase/lipase correlated with grade of injury. Neither amylase nor lipase predicted length of stay or mortality. Maximal amylase was highly predictive of developing a pseudocyst. There seems to be limited value for repetitive routine amylase and lipase levels in the management of pediatric trauma patients with pancreatic injury.


Dec 1, 1975·American Journal of Surgery·J A MoretzG R Williams
Jun 8, 1999·Journal of Pediatric Surgery·M A JobstF P Lynch
Dec 23, 1999·The Journal of Trauma·E P NadlerH R Ford
Jun 29, 2001·The Journal of Trauma·T G Canty, D Weinman
Dec 25, 2003·Journal of Pediatric Surgery·A S W JacombsD T Cass
Dec 28, 2004·American Journal of Surgery·Martin S KellerThomas R Weber
Jul 28, 2006·Pediatric Emergency Care·Andrew J CapraroMark L Waltzman
Aug 19, 2006·The Journal of Trauma·David Patrick MooneyPeter W Forbes
Feb 3, 2007·Journal of Pediatric Surgery·Kelly D MattixL Scherer
Dec 17, 2008·Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention·M Peden
Mar 12, 2009·The Journal of Trauma·Stephen J FentonEric R Scaife

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