Utility of CT in the emergency department in patients with ulcerative colitis

Inflammatory Bowel Diseases
Laurie GashinAdam S Cheifetz

Abstract

Computed tomography (CT) is used in the emergency department (ED) for triage of patients with gastrointestinal complaints. Patients with inflammatory bowel disease undergo radiologic studies for gastrointestinal symptoms and are at risk for excessive ionizing radiation exposure; however, the utility of CT in the ED in patients with ulcerative colitis (UC) is not clear. In this study, we assess the frequency and risk factors for clinically significant CT findings in patients with UC in the ED. We retrospectively reviewed 163 consecutive cases of patients with UC who presented to a tertiary care ED and underwent abdominopelvic CT between June 2008 and December 2011. Using logistic regression, we identified predictors of significant CT findings and derived a model to predict CT scans without clinically significant findings. Of note, 63.2% (103/163) of CT scans had no clinically significant findings. Less than 2% of scans revealed complications related to UC. Predictors of CT scans without clinically significant findings included rectal bleeding or diarrhea (P < 0.001), use of 5-aminosalicylate (P = 0.011), or immunomodulator (P = 0.032). Alternatively, predictors of clinically significant CT findings included nausea and vomiting (...Continue Reading

References

Mar 1, 1987·AJR. American Journal of Roentgenology·E K FishmanS S Siegelman
Jul 1, 1996·AJR. American Journal of Roentgenology·R M GoreF H Miller
May 15, 2004·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Akira FurukawaTsutomu Sakamoto
Apr 13, 2006·Gut·B A Mackalski, C N Bernstein
Apr 14, 2006·Kidney International. Supplement·R Mehran, E Nikolsky
Nov 30, 2007·The New England Journal of Medicine·David J Brenner, Eric J Hall
Jun 20, 2008·The American Journal of Gastroenterology·Joanna M PeloquinEdward V Loftus
Aug 28, 2009·The New England Journal of Medicine·Reza FazelBrahmajee K Nallamothu
Dec 17, 2009·Archives of Internal Medicine·Amy Berrington de GonzálezCharles Land
Aug 4, 2010·Journal of Clinical Gastroenterology·Karen I KroekerRichard N Fedorak
Dec 1, 2010·Radiology·David B LarsonHoward P Forman
Aug 13, 2011·Annals of Emergency Medicine·Keith E KocherBrahmajee K Nallamothu
Sep 29, 2011·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Caroline KernerJames D Lewis
Nov 4, 2011·The New England Journal of Medicine·Silvio Danese, Claudio Fiocchi
Jan 14, 2012·Alimentary Pharmacology & Therapeutics·S ChatuR C G Pollok
Apr 18, 2012·Inflammatory Bowel Diseases·Yoon Suk JungWon Ho Kim
Jul 28, 2012·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Suresh PolaWilliam J Sandborn
Jun 26, 2013·Seminars in Roentgenology·Jeff L FidlerSteven W Trenkner

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Citations

Jul 15, 2015·Inflammatory Bowel Diseases·Shahzaib Nabi
Jul 22, 2015·Inflammatory Bowel Diseases·Laurie Gashin, Adam S Cheifetz
May 3, 2016·Emergency Medicine Clinics of North America·David J CarlbergJeffrey S Dubin
Jun 19, 2016·Annals of Emergency Medicine·Richard T GriffeyAlexandra Gutierrez
May 17, 2017·Inflammatory Bowel Diseases·Geoffrey C NguyenGil Y Melmed
Sep 27, 2018·Journal of Crohn's & Colitis·Jessie J WongK T Park

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