Utility of high b-value (2000 sec/mm2) DWI with RESOLVE in differentiating papillary thyroid carcinomas and papillary thyroid microcarcinomas from benign thyroid nodules

PloS One
Qingjun WangYuanyuan Lu

Abstract

The aim of the study was to evaluate the role of high b-value (2000 sec/mm2) diffusion-weighted imaging (DWI) by using Readout Segmentation of Long Variable Echo-trains (RESOLVE) in differentiating papillary thyroid carcinomas (PTCs) and papillary thyroid microcarcinomas (PTMCs) from benign thyroid nodules. Consecutive patients with thyroid nodules scheduled for surgery underwent high b-value DWI with 3 b-values: 0, 800 and 2000 sec/mm2. Signal intensity ratios (SIRs) of thyroid nodules to adjacent normal thyroid tissue on DWI were measured as: SIRb0, SIRb800 and SIRb2000. Apparent diffusion coefficient (ADC) values based on the 3 different b-values were acquired as: ADCb0-800, ADCb0-2000, and ADCb0-800-2000. The 6 diagnostic indicators were evaluated by receiver operating characteristic (ROC) and diagnostic ability was compared between high b-value DWI and Ultrasound (US). A total of 52 PTCs including 33 PTMCs (38 patients, 8 men and 30 women, aged 45.68 ± 11.93 years) and 62 benign thyroid nodules (46 patients, 7 men and 39 women, aged 48.73 ± 11.98 years) were enrolled into the final statistical analysis. ADCb0-800-2000 had the highest diagnostic ability in differentiating PTCs from benign thyroid nodules with area under cur...Continue Reading

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Citations

Nov 27, 2019·Journal of Magnetic Resonance Imaging : JMRI·Chun-Qiu SuXun-Ning Hong
Feb 16, 2019·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Wei YueJingliang Cheng
Jan 24, 2020·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Minghui SongQueenie Chan
Apr 28, 2021·Magnetic Resonance Imaging Clinics of North America·Felix BoucherAshok Srinivasan

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Methods Mentioned

BETA
biopsy
surgical resection

Software Mentioned

Syngo
RESOLVE
MedCalc
SIR

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