Utility of indigo carmine angiography in patients with critical limb ischemia: Prospective multi-center intervention study (DIESEL-study)

Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
Akihiro HigashimoriYoshiaki Yokoi

Abstract

To assess the efficacy of indigo carmine angiography for wound healing after successful below-the-knee intervention in patients with critical limb ischemia (CLI). A multi-center prospective intervention study was conducted. Fifty-four limbs of 53 patients in Rutherford categories 5 and 6 underwent endovascular therapy (EVT). After successful EVT, 5 mL of indigo carmine was injected through a catheter at the distal popliteal artery and color changes in the foot were evaluated. The results of indigo carmine angiography were divided into three groups: In type I, the color change of the wound was deeper than the surrounding tissue; in type II, the change in wound color was similar to the surrounding tissue; and in type III, no discoloration of the wound was observed by the indigo carmine. The wound healing rates at 3 months were 78% (25/32) for type I, 70% (7/10) for type II, and 42% (5/12) for type III (P for trend = 0.025). Indigo carmine angiography-related complications were not seen. Indigo carmine angiography was found to be a safe and useful procedure to provide visual information on foot perfusion. This dye coloring method demonstrated that after successful angioplasty, the perfused area was made visible at the microcircula...Continue Reading

References

Jan 8, 2011·Journal of Vascular Surgery·Mark F ConradRichard P Cambria
Mar 21, 2012·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Osami KawaradaPeter J Fitzgerald
Jan 29, 2013·Journal of Vascular Surgery·Jonathan D BraunJoseph L Mills
Aug 27, 2013·Annals of Vascular Surgery·Hiroaki TerasakiMaarit Venermo
Aug 27, 2013·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·K IgariT Kawano
Mar 10, 2015·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·T ShirakiM Uematsu
Apr 19, 2015·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Akihiro Higashimori, Yoshiaki Yokoi
Oct 23, 2015·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Akihiro HigashimoriUNKNOWN OLIVE Investigators
Jan 21, 2017·JACC. Cardiovascular Interventions·Makoto UtsunomiyaUNKNOWN OLIVE Investigators

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Citations

Aug 14, 2019·Circulation·Sanjay MisraUNKNOWN American Heart Association Council on Peripheral Vascular Disease; Council on Clinical Cardiology; and Council on Cardiovasc

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