PMID: 9185731Jun 1, 1997Paper

Utility of preoperative radionuclide scanning for primary hyperparathyroidism

The Laryngoscope
C K SinhaT C Huntley

Abstract

This study retrospectively reviews 60 cases of primary hyperparathyroidism, 21 of whom underwent technetium 99 sestamibi scanning and 10 of whom underwent thallium 201/technetium 99 pertechnetate scanning preoperatively. The sestamibi and thallium scans demonstrated an 89.5% and a 62.5% sensitivity rate for adenoma, respectively. Neither scan demonstrated hyperplastic glands well. Although the scans localized adenomatous glands to the correct side well, the ability to localize them more discretely was 68.4% and 62.5%, respectively. In cases of solitary adenoma the effect of an accurate preoperative scan on operative time for bilateral exploration was not significant, whereas the experience of the attending surgeon was significant. Also, the cost of the scans at our institution was greater than the cost of the time saved in performing even unilateral neck exploration. Thus preoperative radionuclide scanning is not cost-effective for the initial exploration of patients with primary hyperparathyroidism and is insufficiently sensitive to make routine unilateral neck exploration for adenoma consistently effective.

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Citations

Jan 6, 1999·The British Journal of Surgery·F PattouC Proye
Jul 21, 2004·Otolaryngologic Clinics of North America·James RudaChristopher S Hollenbeak
Jun 14, 2003·Otolaryngologic Clinics of North America·Greg A Krempl, Jesus E Medina
May 5, 2001·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·E J Kezirian, B Yueh
Mar 5, 2005·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·James M RudaBrendan C Stack
Feb 3, 1999·The Medical Clinics of North America·F R Miller, J L Netterville

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