Abstract
The aim of this study was to address the role of the elasticity index as a possible predictive marker for detecting papillary thyroid carcinoma (PTC) and quantitatively assess shear wave elastography (SWE) as a tool for differentiating PTC from benign thyroid nodules. One hundred and nineteen patients with thyroid nodules undergoing SWE before ultrasound-guided fine needle aspiration and core needle biopsy were analyzed. The mean (EMean), minimum (EMin), maximum (EMax), and standard deviation (ESD) of SWE elasticity indices were measured. Among 105 nodules, 14 were PTC and 91 were benign. The EMean, EMin, and EMax values were significantly higher in PTCs than benign nodules (EMean 37.4 in PTC vs. 23.7 in benign nodules, p = 0.005; EMin 27.9 vs. 17.8, p = 0.034; EMax 46.7 vs. 31.5, p < 0.001). The EMean, EMin, and EMax were significantly associated with PTC with diagnostic odds ratios varying from 6.74 to 9.91, high specificities (86.4%, 86.4%, and 88.1%, respectively), and positive likelihood ratios (4.21, 3.69, and 4.82, respectively). The ESD values were significantly higher in PTC than in benign nodules (6.3 vs. 2.6, p < 0.001). ESD had the highest specificity (96.6%) when applied with a cut-off value of 6.5 kPa. It had a po...Continue Reading
References
Jul 1, 1995·Radiology·A T StavrosG A Sisney
Jul 20, 2004·BMJ : British Medical Journal·Jonathan J Deeks, Douglas G Altman
Dec 6, 2006·Ultrasound Quarterly·Mary C FratesFranklin N Tessler
Feb 5, 2009·The Journal of Clinical Endocrinology and Metabolism·Haixia GuanMingzhao Xing
Oct 29, 2009·Thyroid : Official Journal of the American Thyroid Association·UNKNOWN American Thyroid Association (ATA) Guidelines Taskforce on Thyroid Nodules and Differentiated Thyroid CancerR Michael Tuttle
Nov 6, 2009·Thyroid : Official Journal of the American Thyroid Association·Edmund S Cibas, Syed Z Ali
Oct 1, 2010·The Journal of Clinical Endocrinology and Metabolism·F SebagC Oliver
Dec 3, 2010·Breast Cancer Research : BCR·Andrew EvansAlastair Thompson
Jan 14, 2011·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Won-Jin MoonUNKNOWN Korean Society of Radiology
Dec 28, 2011·European Radiology·Kunwar S S BhatiaAnil T Ahuja
Feb 24, 2012·European Journal of Radiology·Vito CantisaniPaolo Ricci
May 31, 2012·European Radiology·Kunwar S S BhatiaAnil T Ahuja
Oct 4, 2012·European Journal of Radiology·J-B VeyrieresP Petit
Jun 15, 2013·European Journal of Radiology·Vito CantisaniCarlo Catalano
Sep 30, 2014·The Journal of Urology·Katharina BoehmLars Budaeus
Dec 24, 2014·European Journal of Radiology·Ah Young ParkCheong Soo Park
Jan 31, 2015·Radiology·Qiang LuYan Luo
Mar 10, 2015·Thyroid : Official Journal of the American Thyroid Association·Luciana Reck RemontiJorge Luiz Gross
Nov 27, 2015·European Radiology·A C L LamK S S Bhatia
Oct 30, 2016·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Fen WangLi Qing Feng
Citations
Oct 16, 2018·Clinical Hemorheology and Microcirculation·Hui-Xiong XuSu-Jin Zhou
Apr 20, 2020·Journal of Medical Ultrasonics·Shao-Ting HuangYi-Bin Wang
Apr 18, 2021·Journal of Endocrinological Investigation·K Z SwanS J Bonnema