Utilization and outcomes of kidney paired donation in the United States

Transplantation
Dorry L SegevRobert A Montgomery

Abstract

Kidney paired donation (KPD) offers the best transplant option for patients with incompatible live kidney donors. Although studies suggest substantial expansion of the donor pool if fully used, few patients in the United States have undergone KPD. We analyzed the 209 KPD and 89 list paired donation (LPD) transplants reported to United Network for Organ Sharing to better understand access to these modalities, clinical outcomes, and areas of potential expansion. Although many centers offer KPD/LPD, most centers have performed no more than a handful of transplants. As expected, outcomes with KPD/LPD were equivalent to direct donation matched controls. In analyzing current practice, we identified two limitations to KPD in its current use. First, KPD is likely limited now by benefiting mostly patients who are easy to identify and match (such as A donors with B recipients or B donors with A recipients). Second, although some expansion of local KPD availability has reduced travel requirements for patients in those areas, significant room for growth remains. Our results suggest that full utilization of KPD would encourage registration of and improve matching for patients who are more difficult to identify and match (such as highly sens...Continue Reading

References

Jun 12, 1997·The New England Journal of Medicine·L F RossE S Woodle
Apr 30, 2004·The New England Journal of Medicine·Francis L Delmonico
Jun 16, 2004·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Kota TakahashiUNKNOWN Japanese ABO-Incompatible Kidney Transplantation Committee
Sep 16, 2004·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Francis L DelmonicoRichard J Rohrer
Apr 21, 2005·JAMA : the Journal of the American Medical Association·Dorry L SegevRobert A Montgomery
Jul 6, 2005·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Sommer E GentryRobert A Montgomery
Aug 13, 2005·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Marry de KlerkWillem Weimar
Aug 13, 2005·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Inessa KaplanAndrea A Zachary
Sep 16, 2005·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Dorry L SegevRobert A Montgomery
Oct 6, 2005·JAMA : the Journal of the American Medical Association·Robert A MontgomeryDaniel S Warren
Mar 15, 2006·Transplantation·Susan L SaidmanFrancis L Delmonico
Jul 22, 2006·Transplantation·Robert A MontgomeryDorry L Segev
Oct 14, 2006·Kennedy Institute of Ethics Journal·Lainie Friedman Ross
Sep 12, 2007·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·S E GentryR A Montgomery

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Citations

Jan 21, 2010·Immunologic Research·Daniel S Warren, Robert A Montgomery
Sep 10, 2010·The New England Journal of Medicine·Adam W BingamanCathi L Murphey
Feb 1, 2012·Transplantation·John R MontgomeryDorry L Segev
Apr 24, 2013·Journal of Cardiothoracic Surgery·Thomas M SuszynskiKlearchos K Papas
Sep 30, 2010·Clinical Journal of the American Society of Nephrology : CJASN·Francis L WengAnup M Patel
Aug 26, 2014·Medizinische Klinik, Intensivmedizin und Notfallmedizin·G Bond, G A Böhmig
May 7, 2009·Current Opinion in Organ Transplantation·Ilias I N Doxiadis, Frans H J Claas
Jul 14, 2012·Current Opinion in Organ Transplantation·Cathi L Murphey, Adam W Bingaman
Nov 12, 2013·The Surgical Clinics of North America·Meredith J Aull, Sandip Kapur
Jul 31, 2012·Transplantation Proceedings·A Chkhotua
May 23, 2009·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·M D Stegall
Jul 1, 2009·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·F K ButtJ L Veale
Aug 7, 2009·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·S E GentryD L Segev
Mar 28, 2013·Transplant International : Official Journal of the European Society for Organ Transplantation·Krista L Lentine, Dorry L Segev
Mar 13, 2012·Clinical Transplantation·Dorry L SegevL Ebony Boulware
Jan 29, 2011·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·D L SegevR A Montgomery
Apr 23, 2013·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·E A BlumbergUNKNOWN Optimal Testing of the Live Organ Donor Consensus Conference Participants
Feb 27, 2013·Transplant International : Official Journal of the European Society for Organ Transplantation·Vivek B KuteHargovind L Trivedi
Jul 20, 2010·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·B E LonzeR A Montgomery
Feb 13, 2013·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·M L MelcherS Feng
May 3, 2012·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·A W BingamanC L Murphey
Jul 21, 2012·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·M L MelcherJ L Veale
Jun 18, 2014·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·L A Baxter-LoweM L Melcher
May 28, 2015·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·D E FumoM A Rees
Jun 23, 2015·Transplant International : Official Journal of the European Society for Organ Transplantation·Lionel CouziNizam Mamode
Nov 12, 2016·Transplantation Reviews·Ben C Reynolds, Kathryn J Tinckam
Mar 21, 2017·Transplant International : Official Journal of the European Society for Organ Transplantation·Vivek B KuteHargovind L Trivedi
Aug 18, 2009·Current Opinion in Immunology·Frans H J Claas, Ilias I N Doxiadis
Feb 14, 2018·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Courtenay M HolscherDorry L Segev
May 19, 2011·British Medical Bulletin·Robert A Montgomery
Aug 1, 2018·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Courtenay M HolscherDorry L Segev
Apr 23, 2009·Transplantation·Robert A MontgomeryMark Haas
Aug 30, 2008·Transplantation·Marry de Klerk, Willem Weimar
Mar 13, 2019·Clinical Transplantation·Cory R SchaffhausenAjay K Israni
Apr 8, 2010·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Dorry L Segev, Robert A Montgomery
Jan 1, 2014·Canadian Journal of Kidney Health and Disease·Shafi Malik, Edward Cole
Mar 6, 2019·Texas Heart Institute Journal·Mohamed Saleh IsmailNhu Thao Nguyen Galvan
Jun 18, 2010·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·E S WoodleUNKNOWN Paired Donation Network
Jul 11, 2018·World Journal of Transplantation·Vivek B KutePranjal R Modi
Jan 12, 2011·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·A W BingamanK A Newell

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