PMID: 4791483Jul 1, 1973Paper

Utilization of carbon and nitrogen sources by Streptomyces kanamyceticus for kanamycin production

Antimicrobial Agents and Chemotherapy
K Basak, S K Majumdar

Abstract

To select a suitable synthetic medium for kanamycin production, we tested a number of carbon and nitrogen compounds for their effect on growth of Streptomyces kanamyceticus ATCC 12853 as well on kanamycin production. Galactose was found to be the most suitable carbon source, though dextrin, soluble starch, and potato starch gave moderate yields. Sodium nitrate and glycine were adequate nitrogen sources for kanamycin production. There was, however, no direct relation between the growth of the organism and antibiotic formation. The pH of the medium might be an important factor for kanamycin formation, as media giving high kanamycin yields showed an alkaline pH without exception.

References

Jul 1, 1955·Archives of Biochemistry and Biophysics·O K SEBEK

Citations

Jan 1, 1976·Folia Microbiologica·K Basak, S K Majumdar
Oct 1, 1975·Antimicrobial Agents and Chemotherapy·K Basak, S K Majumdar
Dec 3, 2014·Bioresource Technology·Tan-Che Zhou, Jian-Jiang Zhong
Aug 16, 2016·Brazilian Journal of Microbiology : [publication of the Brazilian Society for Microbiology]·Rajesh Kumar MunagantiDattatray M Akkewar

Related Concepts

Alcohols
Vitreous Carbon
Hydrogen-Ion Concentration
Kantrex
Nitrogen
Streptomyces
Carbohydrate Metabolism

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