Utilization of Hyaluronate and Incidence of Septic Knee Arthritis in Adults: Results from the Korean National Claim Registry

Clinics in Orthopedic Surgery
Young-Kyun LeeKyung-Hoi Koo

Abstract

Septic arthritis of the knee has been reported recently in adult patients who were administered hyaluronate. We evaluated the incidence of septic knees and the utilization of hyaluronate in the Korean adult population using nationwide data from the Health Insurance Review and Assessment Service (HIRA). All new admissions to the clinics or hospitals for septic knees were recorded in the HIRA database which was established by the Korean government and covers the Korean population using the International Classification of Diseases-10 revision code. We evaluated the incidence of septic arthritis of the knees in the population above 50 years of age. Hyaluronate prescription data was also collected from the HIRA database. In 2012, the incidence of septic knees was 2.7 per 100,000 persons in men and 4.2 per 100,000 persons in women, respectively. The age-adjusted incidence of septic knees increased by 6.7% per year (95% confidence interval, 3.3 to 10.1), and the annual number of prescriptions of hyaluronate increased about 1.5-fold during the study period. Cautious aseptic technique is required when hyaluronate is administered in adult patients with osteoarthritis of the knee due to the concerns of the risk of septic arthritis.

References

Jun 1, 1976·Annals of the Rheumatic Diseases·J H Newman
Dec 1, 1996·Epidemiology and Infection·D S MorganB J Currie
Aug 1, 1997·Annals of the Rheumatic Diseases·C J KaandorpB A Dijkmans
Jun 12, 1999·Annals of the Rheumatic Diseases·V C WestonM Doherty
Sep 12, 2001·Clinical Orthopaedics and Related Research·J D EvanichJ A Rydlewicz
Apr 8, 2004·The Journal of Bone and Joint Surgery. American Volume·Saam MorshedMichael D Ries
Sep 29, 2007·Annals of the Rheumatic Diseases·A J GeirssonA Víkingsson
Feb 2, 2010·Journal of Korean Medical Science·Inje KimDong Hyun Kim
Mar 9, 2010·Lancet·Catherine J MathewsGerald Coakley
Apr 3, 2010·The Journal of Bone and Joint Surgery. American Volume·John RichmondUNKNOWN American Academy of Orthopaedic Surgeons
Jun 7, 2011·Journal of Bone and Mineral Metabolism·Chanmi ParkYoung-Kyun Lee
Nov 24, 2011·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·Y-K LeeD-Y Kim
May 24, 2012·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·Y-K LeeK-H Koo
Feb 14, 2014·Journal of Bone Metabolism·Sang-Hwan KimChan-Soo Shin
Mar 3, 2015·Clinics in Orthopedic Surgery·Soon Chul LeeSung San Lee

❮ Previous
Next ❯

Software Mentioned

Joinpoint Regression

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Y-K LeeD-Y Kim
Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Y-K LeeK-H Koo
Journal of Korean Medical Science
Young-Kyun LeeKyung-Hoi Koo
© 2021 Meta ULC. All rights reserved