Utilization of lipids during exercise in human subjects: metabolic and dietary constraints

The British Journal of Nutrition
F Brouns, G J van der Vusse

Abstract

During endurance exercise, skeletal muscle relies mainly on both carbohydrate (CHO) and fat oxidation to cover energy needs. Numerous scientific studies have shown that increasing the exercise intensity leads to a progressive utilization of CHO. The latter will induce a state of glycogen depletion which is generally recognized as being a limiting factor for the continuation of strenuous exercise. Different dietary interventions have been proposed to overcome this limitation. A high-CHO diet during periods of intense training and competition, as well as CHO intake during exercise, are known to maintain a high rate of CHO oxidation and to delay fatigue. However, it has been recognized also that enhancing fatty acid (FA) oxidation during exercise induces a reduced rate of glycogen degradation, resulting in an improved endurance capacity. This is most strikingly observed as a result of frequent endurance exercise which improves a number of factors known to govern the FA flux and the oxidative capacity of skeletal muscle. Such factors are: (1) blood flow and capillarization; (2) lipolysis of triacylglycerol (TAG) in adipose tissue and circulating TAG and transport of FA from blood plasma to the sarcoplasm; (3) availability and rate ...Continue Reading

References

Jan 27, 1978·Biochimica Et Biophysica Acta·H Lithell, J Boberg
Nov 1, 1978·Metabolism: Clinical and Experimental·E A NikkiläM Härkönen
Jan 1, 1977·Annals of the New York Academy of Sciences·B Essén
Jun 1, 1977·European Journal of Clinical Investigation·D J HeafL A Carlson
Feb 1, 1979·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·H J GreenP D Gollnick
Apr 15, 1978·European Journal of Applied Physiology and Occupational Physiology·C T DaviesE ZeidiFard
Oct 1, 1977·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·D L CostillD Hoopes
Sep 1, 1976·The American Journal of Physiology·C LinderR O Scow
Feb 1, 1975·Metabolism: Clinical and Experimental·S O FröbergL H Nilsson
Jan 1, 1992·European Journal of Applied Physiology and Occupational Physiology·F AnselmeC Prefaut
Oct 1, 1992·Physiological Reviews·G J van der VusseR S Reneman
Oct 15, 1992·The Biochemical Journal·J E Braun, D L Severson
Oct 1, 1992·Journal of Applied Physiology·D MassicotteC Hillaire-Marcel
Nov 1, 1992·International Journal of Sports Medicine·E J BeckersW H Saris
Jan 1, 1992·Canadian Journal of Physiology and Pharmacology·J Gorski
Oct 1, 1991·International Journal of Sports Medicine·K CollompC Préfaut
Dec 1, 1991·Journal of Applied Physiology·T E Graham, L L Spriet
May 1, 1991·Pflügers Archiv : European journal of physiology·J C McDermottA Bonen
Jan 1, 1991·European Journal of Applied Physiology and Occupational Physiology·S L DoddR Tulley
Apr 1, 1991·Medicine and Science in Sports and Exercise·T J Doubt, S S Hsieh
Oct 8, 1990·Molecular and Cellular Biochemistry·M C LinssenG J van der Vusse
Apr 1, 1990·The American Journal of Physiology·L CampsT Olivecrona
Mar 1, 1990·The Journal of Clinical Investigation·P ArnerJ Bolinder
Jul 1, 1990·The Journal of Nutrition·B R DouglasC B Lamers
Dec 1, 1989·Journal of Applied Physiology·W W WinderP R Vehrs
Oct 1, 1989·International Journal of Sports Medicine·G M JanssenJ D Ross
Dec 1, 1989·Journal of the Neurological Sciences·R S StaronM T Hagerman
Feb 1, 1989·The Journal of Clinical Investigation·B Kiens, H Lithell
May 1, 1989·International Journal of Sports Medicine·F BrounsF ten Hoor
Aug 1, 1989·Medicine and Science in Sports and Exercise·M A TarnopolskyJ R Sutton
Jun 24, 1989·Molecular and Cellular Biochemistry·J B BassingthwaighteJ F Glatz
Oct 1, 1989·Journal of Applied Physiology·R S Mazzeo, P Marshall
Feb 1, 1985·Medicine and Science in Sports and Exercise·W W Winder
Jan 1, 1986·Diabetes/metabolism Reviews·R L Terjung, H Kaciuba-Usciłko
Aug 1, 1986·Biochemical Society Transactions·C L Hoppel, A T Davis
Jun 1, 1988·Canadian Journal of Physiology and Pharmacology·C CôtéJ A Faulkner
Sep 1, 1987·Journal of Applied Physiology·J C McDermottA Bonen
Feb 1, 1986·Journal of Applied Physiology·B F HurleyJ O Holloszy
Mar 1, 1986·The Journal of Clinical Investigation·G AhlborgP Felig

❮ Previous
Next ❯

Citations

Jul 11, 2001·Trends in Endocrinology and Metabolism : TEM·A StahlH F Lodish
Mar 30, 2002·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·C Leigh BroadhurstWalter F Schmidt
Dec 16, 1998·The British Journal of Nutrition·W H SarisM Vogel
Jun 5, 2003·British Journal of Sports Medicine·F DegoutteE Filaire
Dec 5, 2012·Nutrition Reviews·Tom M McLellan, Harris R Lieberman
Sep 28, 2010·Nutrition·Wei LiuXin-Yong Song
Aug 28, 2009·Research in Veterinary Science·Sumei ZhaoSixiang Zou
Oct 4, 2005·European Journal of Internal Medicine·Ernesto VinciMariano Malaguarnera
Oct 23, 2015·BioMed Research International·Evasio PasiniFrancesco S Dioguardi
Oct 6, 2011·Journal of Microencapsulation·Weilin LiuJiahong Su
May 6, 2015·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Camila Garcia MarquesMaria Fernanda Cury-Boaventura
Sep 20, 2002·Acta Veterinaria Hungarica·A SzabóZs Szendró
Aug 6, 2011·Prostaglandins, Leukotrienes, and Essential Fatty Acids·Ryan W Mitchell, Grant M Hatch
Sep 17, 2009·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·S M ZhaoS Z Gao
Jan 16, 2004·Scandinavian Journal of Medicine & Science in Sports·Ola RønsenArne T Høstmark
Nov 1, 2006·NMR in Biomedicine·Chris BoeschFritz Schick
Oct 2, 2002·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·I HarantD Rivière
Jun 25, 2003·European Journal of Clinical Nutrition·D KönigR Rauramaa
May 18, 2005·Sports Medicine·Robert G McMurray, Anthony C Hackney
Jun 20, 2018·Journal of the International Society of Sports Nutrition·Mark Christian ManioKazuo Inoue
Mar 29, 2001·The American Journal of Clinical Nutrition·I Bourdel-MarchassonE Thiaudière
Aug 27, 2015·Journal of Strength and Conditioning Research·Leonardo V AndreatoEmerson Franchini
Sep 10, 2002·Medicine and Science in Sports and Exercise·John A Hawley
Dec 30, 2020·Biomolecules·Antonella MuscellaSanto Marsigliante

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.