Utilizing temporal data abstraction for data validation and therapy planning for artificially ventilated newborn infants

Artificial Intelligence in Medicine
Silvia MikschF Paky

Abstract

Medical diagnosis and therapy planning at modern intensive care units (ICUs) have been refined by the technical improvement of their equipment. However, the bulk of continuous data arising from complex monitoring systems in combination with discontinuously assessed numerical and qualitative data creates a rising information management problem at neonatal ICUs (NICUs). We developed methods for data validation and therapy planning which incorporate knowledge about point and interval data, as well as expected qualitative trend descriptions to arrive at unified qualitative descriptions of parameters (temporal data abstraction). Our methods are based on schemata for data-point transformation and curve fitting which express the dynamics of and the reactions to different degrees of parameters' abnormalities as well as on smoothing and adjustment mechanisms to keep the qualitative descriptions stable. We show their applicability in detecting anomalous system behavior early, in recommending therapeutic actions, and in assessing the effectiveness of these actions within a certain period. We implemented our methods in VIE-VENT, an open-loop knowledge-based monitoring and therapy planning system for artificially ventilated newborn infants....Continue Reading

References

Feb 1, 1993·Artificial Intelligence in Medicine·S UckunD P Lindstrom
Feb 1, 1993·Artificial Intelligence in Medicine·G W RutledgeL M Fagan
Jul 1, 1996·Artificial Intelligence in Medicine·Y Shahar, M A Musen
Dec 1, 1995·Artificial Intelligence in Medicine·I J HaimowitzI S Kohane

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Citations

Nov 1, 1994·International Journal of Clinical Monitoring and Computing·S Uckun
Jul 25, 2000·Artificial Intelligence in Medicine·D CalveloP Ravaux
Jul 25, 2000·Artificial Intelligence in Medicine·K MorikM Imboff
Aug 11, 2000·Artificial Intelligence in Medicine·C D Spyropoulos
Jul 27, 2001·Artificial Intelligence in Medicine·W Horn
Oct 23, 1997·Artificial Intelligence in Medicine·J Hunter
Oct 21, 1998·Artificial Intelligence in Medicine·M DojatD Fontaine
Apr 14, 2000·American Journal of Respiratory and Critical Care Medicine·M DojatL Brochard
Oct 28, 2006·Journal of the American Medical Informatics Association : JAMIA·Svetla GadzhanovaLorenzo Ponte
Dec 22, 2007·Journal of the American Medical Informatics Association : JAMIA·Marion VerduijnBas A J M de Mol
Mar 6, 2009·Journal of Clinical Monitoring and Computing·Fleur T Tehrani, Soraya Abbasi
May 20, 2009·Best Practice & Research. Clinical Anaesthesiology·Michael ImhoffRoland Fried
Sep 5, 2008·Artificial Intelligence in Medicine·Fleur T Tehrani, James H Roum
Apr 30, 2008·Artificial Intelligence in Medicine·Susana B MartinsMary K Goldstein
Aug 19, 2007·Artificial Intelligence in Medicine·Marion VerduijnBas A J M de Mol
Jul 4, 2009·IEEE Transactions on Pattern Analysis and Machine Intelligence·John A QuinnNeil McIntosh
Nov 13, 2007·IEEE Transactions on Visualization and Computer Graphics·Wolfgang AignerChristian Tominski
Oct 3, 2006·Artificial Intelligence in Medicine·Michael Stacey, Carolyn McGregor
Apr 23, 2005·The Cochrane Database of Systematic Reviews·K TanS J Newell
Apr 25, 2006·Anesthesia and Analgesia·Michael Imhoff, Silvia Kuhls
Jul 5, 2011·Journal of the American Medical Informatics Association : JAMIA·Phil Gooch, Abdul Roudsari
Feb 2, 2022·Medical & Biological Engineering & Computing·Maryam BoumrahAmina Radgui

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