UV and pH-responsive supra-amphiphiles driven by combined interactions for controlled self-assembly behaviors

Soft Matter
Shangyang LiChun Wang

Abstract

In order to fabricate a novel supra-amphiphile with multiple stimulus properties, we developed the strategy of introducing a bi-functional linker to bridge the hydrophilic and hydrophobic building blocks together, by utilizing more than one kind of interaction. We characterized the assembled structure and morphology of the supra-amphiphile using transmission electron microscopy (TEM), dynamic light scattering (DLS) and X-ray diffraction (XRD). 1H NMR and UV-vis spectroscopy studies revealed that the amphiphile was constructed by the effect of host-guest recognition and a dynamic covalent bond, which could be switched ''on'' and ''off'' via UV irradiation and pH variation stimuli, respectively. This responsiveness realized finely controllable self-assembly behaviors of the supra-amphiphile, which was thus able to encapsulate and release the drug model rhodamine B.

References

May 26, 2004·International Journal of Pharmaceutics·Erhan Pişkin
Aug 19, 2006·Science·Yingxin LiuCharles L Liotta
Aug 1, 2007·Chemistry : a European Journal·Bo JingHuayu Qiu
Nov 17, 2007·Langmuir : the ACS Journal of Surfaces and Colloids·Jiong ZouMing Jiang
Mar 7, 2008·Journal of Controlled Release : Official Journal of the Controlled Release Society·Chaoliang HeDoo Sung Lee
Dec 31, 2008·Angewandte Chemie·Rémi NguyenNicolas Giuseppone
Jul 25, 2009·Langmuir : the ACS Journal of Surfaces and Colloids·Yapei WangAlexander V Kabanov
Jun 23, 2010·Journal of the American Chemical Society·Qiang YanYingwu Yin
Aug 13, 2010·The Journal of Physical Chemistry. B·Qiuhong LiFumin Ma
Oct 5, 2010·Chemical Society Reviews·Xi Zhang, Chao Wang
Mar 18, 2011·Angewandte Chemie·Christophe B MinkenbergJan H van Esch
Jan 17, 2012·Accounts of Chemical Research·Chao WangXi Zhang
Jan 20, 2012·Accounts of Chemical Research·Renhao DongJingcheng Hao
Jun 21, 2012·Chemical Communications : Chem Comm·Mouchumi Bhuyan, Burkhard Koenig
Oct 23, 2012·Journal of the American Chemical Society·Shiki YagaiYoshihiro Kikkawa
Dec 1, 2012·The Journal of Physical Chemistry. B·Tao SunAiyou Hao
Jun 12, 2013·Chemical Society Reviews·Yinghua JinWei Zhang
Jun 26, 2013·Journal of the American Chemical Society·Qunpeng DuanLeyong Wang
Jul 26, 2013·Chemical Society Reviews·A SorrentiR M Ortuño
Mar 13, 2014·Langmuir : the ACS Journal of Surfaces and Colloids·Yuetong KangXi Zhang
Feb 24, 2015·Chemical Reviews·Da-Hui QuHe Tian
Mar 25, 2015·Journal of the American Chemical Society·Yi-Xuan WangYu Liu
Apr 14, 2017·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Tao SunChen Jiang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.