UV-induced inactivation rates for airborne Mycobacterium bovis BCG

Journal of Occupational and Environmental Hygiene
Jordan Peccia, Mark Hernandez

Abstract

Engineering ultraviolet irradiation systems as a control against infectious airborne diseases requires a knowledge of intrinsic ultraviolet (UV) inactivation rates of airborne bacteria. Ultraviolet inactivation rates for airborne Mycobacterium bovis bacillus Calmette-Guérin (BCG) were determined at 50% and 95% relative humidity (RH) in a 0.8 m3 bioaerosol reactor. Ultraviolet inactivation response of waterborne M. bovis BCG pure cultures was also determined. At 50% RH the airborne UV inactivation rates observed were two times greater than those observed in saturated air (RH = 95%), and rates at 95% RH were similar to those observed in otherwise identical cultures suspended in water. Intrinsic UV inactivation rates for M. bovis BCG were statistically similar to rates observed for Mycobacterium parafortuitum at 50% and 95% RH, indicating that M. parafortuitum is a valid surrogate for studying airborne UV responses of M. bovis BCG and Mycobacterium tuberculosis. Results also confirm that UV inactivation responses for bacteria suspended in water cannot be used to estimate UV dose response in unsaturated air.

References

Dec 1, 1993·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·E A Nardell
Jul 1, 1996·Applied and Environmental Microbiology·S TerzievaK P Brenner
Jan 1, 1996·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·W W SteadC Hartnett
Aug 14, 1999·Applied Occupational and Environmental Hygiene·M Nicas, S L Miller
May 31, 2001·Journal of the American Geriatrics Society
Aug 30, 2001·Applied and Environmental Microbiology·J Peccia, M Hernandez
Jan 10, 2002·Environmental Health Perspectives·Gwangpyo KoHarriet A Burge

❮ Previous
Next ❯

Citations

Dec 25, 2012·The Science of the Total Environment·Eui-Seok ChongJae Hee Jung
Mar 1, 2012·The Science of the Total Environment·Gi Byoung HwangGwi-Nam Bae
Sep 9, 2010·The Science of the Total Environment·Gi Byoung HwangByung Uk Lee
Jun 3, 2009·Letters in Applied Microbiology·J DonaghyM T Rowe
Oct 17, 2006·Journal of Applied Microbiology·Z Bohrerova, K G Linden
May 21, 2013·Photochemistry and Photobiology·Edward NardellDavid H Sliney
May 15, 2015·PloS One·Gi Byoung HwangJae Hee Jung
Feb 13, 2020·BMC Infectious Diseases·Wai SzetoDennis Y C Leung
Sep 8, 2007·Environmental Science & Technology·Christopher M Walker, Gwangpyo Ko

❮ Previous
Next ❯

Methods Mentioned

BETA
irradiate

Software Mentioned

Excel

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.