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V lambda and J lambda-C lambda gene segments of the human immunoglobulin lambda light chain locus are separated by 14 kb and rearrange by a deletion mechanism

European Journal of Immunology

Jun 1, 1991

Gabriele Combriato, H Gustav Klobeck

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Abstract

We have cloned a region of 124 kb of the human immunoglobulin lambda light chain locus on chromosome 22 encompassing seven V lambda and seven J-C lambda gene segments. No further C lambda gene segment was found in a region of 35 kb downstream of C lambda 7, which encodes the Ke+Oz- isot...read more

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    • References19
    • Citations48
    • References19
    • Citations48
  • V lambda and J lambda-C lambda gene segments of the human immunoglobulin lambda light chain locus are separated by 14 kb and rearrange by a deletion mechanism

    European Journal of Immunology

    Jun 1, 1991

    Gabriele Combriato, H Gustav Klobeck

    PMID: 1904362

    DOI: 10.1002/eji.1830210627

    Abstract

    We have cloned a region of 124 kb of the human immunoglobulin lambda light chain locus on chromosome 22 encompassing seven V lambda and seven J-C lambda gene segments. No further C lambda gene segment was found in a region of 35 kb downstream of C lambda 7, which encodes the Ke+Oz- isot...read more

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    Paper Details
    References
    • References19
    • Citations48
    • References19
    • Citations48
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