Vaccination for asthma exacerbations

Internal Medicine Journal
P G Bardin

Abstract

Most asthma exacerbations are caused by common cold virus infections, predominantly rhinovirus infections. Full protection against repeat infections with the same rhinovirus serotype is given by serum neutralizing antibody, but cross-reactive antibody developed against other serotypes could yield partial protection and result in attenuated cold and airway symptoms. It is proposed that vaccine-mediated induction of cross-reactive antibody might not prevent rhinovirus infections but might reduce severe asthma symptoms and exacerbations.

References

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Citations

Sep 2, 2005·Respirology : Official Journal of the Asian Pacific Society of Respirology·Patricia J LyellPhilip G Bardin
Jul 29, 2010·Respirology : Official Journal of the Asian Pacific Society of Respirology·Gary P Anderson
May 19, 2005·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·S KlingP Bardin
Oct 21, 2016·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Varpu Elenius, Tuomas Jartti

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