Vaccines based on virus-like nano-particles for use against Middle East Respiratory Syndrome (MERS) coronavirus.

Vaccine
Alireza HashemzadehMajid Khazaei

Abstract

Recent advances in virus-like nanoparticles against Middle East respiratory syndrome-related coronavirus (MERS-CoV) can initiate vaccine production faster for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), while ensuring the safety, easy administration, and long-term effects. Patients with this viral pathogen suffer from excess mortality. MERS-CoV can spread through bioaerosol transmission from animal or human sources. The appearance of an outbreak in South Korea sparked off a strong urge to design strategies for developing an effective vaccine since the emergence of MERS-CoV in 2012. Well unfortunately, this is an important fact in virus risk management. The studies showed that virus-like nanoparticles (VLPs) could be effective in its goal of stopping the symptoms of MERS-CoV infection. Besides, due to the genetic similarities in the DNA sequencing of SARS-CoV-2 with MERS-CoV and the first identified severe acute respiratory syndrome (SARS-CoV) in China since 2002/2003, strategic approaches could be used to manage SARS-CoV 2. Gathering the vital piece of information obtained so far could lead to a breakthrough in the development of an effective vaccine against SARS-CoV-2, which is prioritized and focussed by the...Continue Reading

Citations

Mar 23, 2021·Medicine in Drug Discovery·Nikky GoelSunil Kumar Khare
Jun 1, 2021·Medicine in Drug Discovery·Tahereh Seifi, Ali Reza Kamali
Jul 3, 2021·Frontiers in Genetics·Md ZeyaullahRazi Ahmad

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