Vaccines for preventing malaria (SPf66).

The Cochrane Database of Systematic Reviews
P Graves, H Gelband

Abstract

A malaria vaccine is badly needed. SPf66 was one of the earliest vaccines developed. It is a synthetic peptide vaccine containing antigens from the blood stages of malaria linked together with an antigen from the sporozoite stage, and is targeted mainly against the blood (asexual) stages. To assess the effect of SPf66 malaria vaccines against Plasmodium falciparum, P. vivax, P. malariae, and P. ovale in preventing infection, disease, and death. We searched the Cochrane Infectious Diseases Group Specialized Register (September 2005), CENTRAL (The Cochrane Library 2005, Issue 3), MEDLINE (1966 to September 2005), EMBASE (1980 to September 2005), LILACS (1982 to September 2005), Science Citation Index (1981 to September 2005), and reference lists of articles. We also contacted organizations and researchers in the field. Randomized and quasi-randomized controlled trials comparing SPf66 vaccine with placebo or routine antimalarial control measures in people of any age receiving an artificial challenge or natural exposure to malaria infection (any species). Two people independently assessed trial quality and extracted data, including adverse events. Results were expressed as relative risks (RR) with 95% confidence intervals (CI). Ten...Continue Reading

References

Aug 19, 1995·Lancet·U D'AlessandroG A Targett
May 1, 1996·Revista Da Sociedade Brasileira De Medicina Tropical·M UrdanetaM Boulos
Sep 1, 1996·Revista Da Sociedade Brasileira De Medicina Tropical·M UrdanetaM Boulos
Aug 1, 1996·Annals of Tropical Medicine and Parasitology·U D'Alessandro
May 1, 1997·The American Journal of Tropical Medicine and Hygiene·F NostenD G Heppner
Apr 18, 1998·The American Journal of Tropical Medicine and Hygiene·M UrdanetaM Boulos
Oct 28, 1998·The American Journal of Tropical Medicine and Hygiene·G L MasindeP E Duffy
Jul 14, 1999·Tropical Medicine & International Health : TM & IH·C J AcostaP L Alonso
Jul 14, 1999·Tropical Medicine & International Health : TM & IH·D M SchellenbergP L Alonso
Jul 27, 1999·Parasite Immunology·W G MetzgerB M Greenwood
Aug 18, 1999·Transactions of the Royal Society of Tropical Medicine and Hygiene·M HaywoodB Greenwood
May 5, 2000·The Cochrane Database of Systematic Reviews·P Graves, H Gelband
Sep 6, 2000·Parasite Immunology·C M GalindoP L Alonso
Jul 7, 2001·BMJ : British Medical Journal·P JüniM Egger
Feb 8, 2002·Nature·Thomas L Richie, Allan Saul
Jan 22, 2003·The Cochrane Database of Systematic Reviews·P Graves, H Gelband
Jun 3, 2004·The Lancet Infectious Diseases·Simon I HayRobert W Snow
Oct 17, 2006·Parasitology Today·P GravesP Garner
Oct 21, 2006·The Cochrane Database of Systematic Reviews·P Graves, H Gelband
Oct 21, 2006·The Cochrane Database of Systematic Reviews·P Graves, H Gelband

❮ Previous
Next ❯

Citations

May 28, 2013·BioMed Research International·Elena MataJosé Luis Pedraz
Jan 11, 2012·Malaria Journal·Lauren SchwartzVasee S Moorthy
Oct 23, 2013·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Lars G HemkensJohn P A Ioannidis
May 3, 2012·Mediterranean Journal of Hematology and Infectious Diseases·Alberto L García-BasteiroPedro L Alonso
Jul 1, 2011·Tropical Parasitology·Se DamodaranSuresh Chandra Pradhan
Apr 8, 2009·European Journal of Immunology·Michael F Good
Oct 21, 2006·The Cochrane Database of Systematic Reviews·P Graves, H Gelband
Jul 9, 2010·Journal of Leukocyte Biology·Matthew B B McCall, Robert W Sauerwein
Feb 9, 2008·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
Oct 21, 2006·The Cochrane Database of Systematic Reviews·P Graves, H Gelband
Apr 15, 2008·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·Clarissa ValimDavid Wypij
Sep 5, 2014·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·S F Østerhus
Feb 3, 2016·FEMS Microbiology Reviews·James G BeesonJack S Richards
Dec 13, 2019·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·Wolfram Gottfried MetzgerCarsten Köhler
May 7, 2009·Immunology and Cell Biology·Jack S Richards, James G Beeson
Dec 3, 2009·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Francesca GotschLami Yeo
Mar 25, 2014·The Journal of Immunology : Official Journal of the American Association of Immunologists·Weiguo CuiSusan M Kaech
Jul 16, 2020·Vaccines·Mariusz SkwarczynskiWaleed M Hussein
Apr 15, 2021·Tropical Diseases, Travel Medicine and Vaccines·Esteban Ortiz-PradoAndrés López-Cortés

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antimalarial Agents (ASM)

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.

Antimalarial Agents

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.

Related Papers

The Cochrane Database of Systematic Reviews
P Graves, H Gelband
The Cochrane Database of Systematic Reviews
P Graves, H Gelband
The Cochrane Database of Systematic Reviews
P Graves, H Gelband
Nihon rinsho. Japanese journal of clinical medicine
K Tanabe
© 2022 Meta ULC. All rights reserved