Vaginal bleeding during pregnancy and preterm birth

American Journal of Epidemiology
Juan YangJ M Thorp

Abstract

This study investigated the relation between self-reported vaginal bleeding during pregnancy and preterm birth in a prospective cohort of 2,829 pregnant women enrolled from prenatal clinics between 1995 and 2000 in central North Carolina. The overall association between vaginal bleeding and preterm birth was modest (risk ratio (RR) = 1.3, 95% confidence interval (CI): 1.1, 1.6). Bleeding in the first trimester only was associated with earlier preterm birth (< or =34 weeks' gestation) (RR = 1.6, 95% CI: 1.1, 2.4) and preterm birth due to preterm premature rupture of the membranes (PPROM) (RR = 1.9, 95% CI: 1.1, 3.3). Bleeding in both trimesters was associated with preterm birth due to preterm labor (RR = 3.6, 95% CI: 1.9, 6.8). Bleeding of multiple episodes, on multiple days, and with more total blood loss was associated with an approximate twofold increased risk of earlier preterm birth, PPROM, and preterm labor. In contrast, bleeding in the second trimester only, of a single episode, on a single day, and with less total blood loss was not associated with any category of preterm birth. Vaginal bleeding was not associated with preterm birth among African Amercians (RR = 1.2, 95% CI: 0.9, 1.7). This study indicates that more inte...Continue Reading

References

Jan 1, 1979·Acta Obstetricia Et Gynecologica Scandinavica·P Jouppila
Sep 1, 1992·Annals of Epidemiology·S M Yu, D A Nagey
Dec 1, 1992·British Journal of Obstetrics and Gynaecology·P SipiläL Von Wendt
Feb 1, 1991·American Journal of Obstetrics and Gynecology·D A SavitzJ M Thorp
Sep 1, 1990·Epidemiology·J W Kuzma, K D Lindsted
Jul 1, 1990·American Journal of Obstetrics and Gynecology·J H HargerB F Polk
Apr 1, 1989·American Journal of Epidemiology·B Strobino, J Pantel-Silverman
Jun 1, 1972·American Journal of Obstetrics and Gynecology·J R Scott
Jun 1, 1983·International Journal of Epidemiology·G S BerkowitzM Baras
Jan 1, 1994·Paediatric and Perinatal Epidemiology·C V Ananth, D A Savitz
Dec 1, 1995·European Journal of Obstetrics, Gynecology, and Reproductive Biology·S M AxelsenN J Secher
Mar 21, 1998·American Journal of Obstetrics and Gynecology·C C SignoreD S Richards
Feb 13, 1999·Paediatric and Perinatal Epidemiology·D A SavitzB Eucker
Mar 17, 1999·Acta Obstetricia Et Gynecologica Scandinavica·C C Chan, W W To
May 27, 1999·Journal of Perinatal Medicine·C J Lockwood, E Kuczynski
Mar 30, 2000·Primary Care·J D Alexander, F D Schneider
Nov 22, 2001·American Journal of Obstetrics and Gynecology·M A ElovitzM Phillippe
Dec 4, 2001·The Journal of Maternal-fetal Medicine·T RosenC J Lockwood
Aug 19, 2003·Human Reproduction·E W HarvilleC R Weinberg
Sep 10, 2003·Emergency Medicine Clinics of North America·Paolo T Coppola, Marco Coppola

❮ Previous
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Citations

May 8, 2010·Archives of Gynecology and Obstetrics·U ElaveyiniK Suryaprakasa Rao
Jan 17, 2014·Journal of Obstetrics and Gynaecology of India·Maryam Sadat Hosseini, Soghra Yaghoubipour
Mar 10, 2009·Human Reproduction Update·R H F van OppenraaijUNKNOWN ESHRE Special Interest Group for Early Pregnancy (SIGEP)
Nov 6, 2009·Obstetrics and Gynecology·Reem HasanKatherine E Hartmann
Nov 23, 2013·Ultrasound Quarterly·Ann E PodraskyCarolyn M Zelop
Jan 10, 2008·Taiwanese Journal of Obstetrics & Gynecology·Chung-Chin LoTai-Ho Hung
Apr 7, 2009·Obstetrics and Gynecology Clinics of North America·Andra H James
Mar 11, 2009·European Journal of Obstetrics, Gynecology, and Reproductive Biology·J PolettiniM G Silva
Jan 9, 2007·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Rydhwana HossainMichelle A Williams
Mar 31, 2015·Journal of Perinatal Medicine·Iwona SzymusikMiroslaw Wielgos
Jun 3, 2011·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Devon IndigAnne Saxton
Jan 3, 2013·Pediatric Dermatology·Xiao Dong ChenXiao Xi Lin
Jan 19, 2012·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Sik Wing YeungRachel Y K Cheung
Mar 23, 2012·The Journal of Obstetrics and Gynaecology Research·Lida Moghaddam BanaemNarges Aliyan Moghadam
Jan 19, 2010·Paediatric and Perinatal Epidemiology·Reem HasanDonna D Baird
Dec 1, 2009·BJOG : an International Journal of Obstetrics and Gynaecology·L SaraswatS Bhattacharya
Jan 16, 2010·BJOG : an International Journal of Obstetrics and Gynaecology·J W GarganoR Fisher
Oct 21, 2011·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Lu SunRong Xu
Oct 27, 2012·American Journal of Obstetrics and Gynecology·Jessica A McPhersonAlison G Cahill
Dec 3, 2011·American Journal of Obstetrics and Gynecology·Devon M Ramaeker, Hyagriv N Simhan
Apr 4, 2006·American Journal of Obstetrics and Gynecology·Kim A BoggessJames D Beck
Jan 15, 2008·American Journal of Obstetrics and Gynecology·Kathleen A WittelsCarlos A Camargo
Apr 29, 2008·American Journal of Obstetrics and Gynecology·Craig V Towers, Amy E Burkhart
Nov 18, 2016·Reproductive Sciences·Michael P SmrtkaChad A Grotegut
Feb 24, 2017·Risk Analysis : an Official Publication of the Society for Risk Analysis·Gulcan Cil, Trudy Ann Cameron
May 15, 2007·Journal of Occupational and Environmental Medicine·Gunild M FreyAndreas Zober
Apr 30, 2005·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·E JauniauxG J Burton
Jul 14, 2005·Haemophilia : the Official Journal of the World Federation of Hemophilia·A H James
Aug 25, 2017·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Lindsay Kennedy ParrishEmily A DeFranco
Sep 21, 2018·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Hadel WatadDoron Kabiri
Jun 12, 2020·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Teresa CoboBo Jacobsson
Aug 15, 2019·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Hiroshi KawamuraNobuaki Mitsuda
Sep 9, 2020·Archives of Gynecology and Obstetrics·Chaitali Ghosh, Martha Wojtowycz
Oct 24, 2009·Cadernos de saúde pública·Ana Maria Rigo SilvaDarli Antonio Soares
Dec 15, 2010·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·David N Hackney, J Christopher Glantz
Dec 24, 2018·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Hongchen ZhengXiaohong Liu
Apr 17, 2019·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Asuman InanNicholas J Beeching
Mar 20, 2019·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·M Al-MemarT Bourne
Dec 4, 2019·Emergency Medicine Australasia : EMA·Stephanie Yc SeeDiana Egerton-Warburton
Mar 23, 2021·The Journal of Obstetrics and Gynaecology Research·Sufen LiuWendi Wang
Jul 21, 2021·Pediatric Research·Dario EliasLucas G Gimenez
Jul 31, 2021·Archives of Gynecology and Obstetrics·Anat LavieHaim Arie Abenhaim

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