Vaginal carcinoma in a female-to-male transsexual

The Journal of Sexual Medicine
Thilo Ludwig SchenckRiccardo Enzo Giunta

Abstract

Sex reassignment surgery (SRS) can be considered a reasonable and secure treatment for transsexualism, today. Because the population of patients who have received SRS is growing steadily, it can be expected that the number of patients who present with diseases specific to their original gender will increase as well. In female-to-male transsexuals, vaginal cancer has not been reported so far. This article reports, to our knowledge, the first case of a female-to-male transsexual who developed vaginal cancer. Eighteen years after receiving female-to-male SRS, the patient presented with vaginal cancer, which infiltrated rectum and bladder and also showed involvement of inguinal lymph nodes. Surgery consisted of an anterior and posterior pelvic demolition and extended lymphadenectomy with preservation of the penoid and reconstruction of the pelvic defect with multiple flaps. The tumor was removed completely (R0), and 2 years after surgery, the patient has no signs or symptoms of tumor recurrence and enjoys good quality of life. In SRS patients, diseases of their original gender should always be considered and patients should be encouraged to participate in screening programs. When choosing the surgical approach for SRS, the risks fo...Continue Reading

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Citations

Apr 30, 2014·The Journal of Sexual Medicine·Louis Gooren, Paul Lips
Feb 28, 2015·Acta Obstetricia Et Gynecologica Scandinavica·Hans W TrumLouis J Gooren
Mar 1, 2011·American Journal of Obstetrics and Gynecology·Renata R UrbanDaniel S Kapp
May 1, 2018·BJOG : an International Journal of Obstetrics and Gynaecology·R JointS Cameron
Jun 21, 2018·Reviews in Endocrine & Metabolic Disorders·Louis J Gooren, Guy T'Sjoen
May 10, 2017·Epidemiologic Reviews·Hayley BraunMichael Goodman
Apr 24, 2014·Current Opinion in Endocrinology, Diabetes, and Obesity·Louis J Gooren
Oct 3, 2020·Gynecologic Oncology·Ashley E StenzelKristen D Starbuck

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