Vaginal Lactobacillus: biofilm formation in vivo - clinical implications

International Journal of Women's Health
G Ventolini

Abstract

Vaginal lactobacilli provide protection against intrusive pathogenic bacteria. Some Lactobacillus spp. produce in vitro a thick, protective biofilm. We report in vivo formation of biofilm by vaginal Lactobacillus jensenii. The biofilm formation was captured in fresh wet-mount microscopic samples from asymptomatic patients after treatment for recurrent bacterial vaginitis. In vivo documentation of biofilm formation is in our opinion noteworthy, and has significant clinical implications, among which are the possibility to isolate, grow, and therapeutically utilize lactobacilli to prevent recurrent vaginal infections and preterm labor associated with vaginal microbial pathogens.

Citations

May 27, 2016·Scientific Reports·Natalia Schlabritz-LoutsevitchGary Ventolini
May 6, 2016·Archives of Microbiology·María Cecilia Leccese TerrafMaría Elena Fátima Nader-Macías
Mar 27, 2020·BMC Microbiology·Stacy MartinezNatalia Schlabritz-Loutsevitch
Mar 31, 2019·FEMS Microbiology Letters·Kanwal AzizArsalan Zaidi
Apr 8, 2020·Frontiers in Cellular and Infection Microbiology·Hyunsul JungMarleen M Kock
Nov 16, 2021·Frontiers in Microbiology·Carola ParolinBeatrice Vitali

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biopsy

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