Vaginal rhabdomyosarcoma in a dog

Veterinary Pathology
K SuzukiT Sato

Abstract

A 10-year-old, female, mongrel showed hemorrhage from vulva. By magnetic resonance image (MRI) and endoscopic examination, a multipapillary mass with a grape-like appearance was found around the urethral opening. Histologically, the mass consisted of variable-sized round-, spindle-to-polygonal-shaped tumor cells including many multinuclear cells. Mitotic figures were also frequently observed. In some areas, that tumor cells were loosely arranged, with intercellular myxoid components. Immunohistochemically, these tumor cells were strongly positive for vimentin and focally positive for desmin but negative for myoglobin. Thus, the case was diagnosed as a relatively poorly differentiated botryoid rhabdomyosarcoma by the macroscopic, histopathologic, and immunohistochemical identification. This is the first report of botryoid rhabdomyosarcoma developing in the vagina of a dog.

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Citations

May 13, 2010·The Journal of Veterinary Medical Science·Marcello Rodrigues da RozaMárcia Cristina da Costa Miguel
Aug 11, 2012·Journal of Comparative Pathology·J N BoeloniN M Ocarino
Mar 28, 2008·Veterinary Clinical Pathology·Seth ChapmanDavid Calise
Mar 31, 2015·The Veterinary Clinics of North America. Small Animal Practice·Silke Hecht
Mar 6, 2008·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Ji-Young YheeJung-Hyang Sur
Nov 8, 2011·Journal of the American Animal Hospital Association·Laura A Snyder, Helen Michael
Mar 5, 2011·Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians·Margarita Woc-ColburnCarlos R Sanchez
Sep 21, 2013·Journal of the American Animal Hospital Association·Andrea WeissmanShannon P Holmes
Sep 7, 2018·The Journal of Veterinary Medical Science·Du-Min GoDae-Yong Kim

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