Vagus nerve-preserving versus conventional laparoscopic splenectomy and azygoportal disconnection

Surgical Endoscopy
Dou-Sheng BaiGuo-Qing Jiang

Abstract

Conventional open and conventional laparoscopic splenectomy and azygoportal disconnection (CLSD) result in poor quality of life because of damage to the vagal nerve. We have developed vagus nerve-preserving laparoscopic splenectomy and azygoportal disconnection (VLSD). This study aimed to evaluate whether VLSD is effective and safe, and to determine whether a reduction in the incidence of postoperative complications improves postoperative quality of life compared with CLSD. We retrospectively evaluated outcomes in 72 cirrhotic patients with portal hypertensive bleeding and secondary hypersplenism who underwent CLSD (n = 40) or VLSD (n = 32) between April 2015 and December 2016. Their demographic, intraoperative, and postoperative variables were compared. No patients required conversion to laparotomy in CLSD and VLSD. There was no difference in estimated intraoperative blood loss, volume of intraoperative blood transfused, time to first flatus, time to off-bed activity, and postoperative hospital stay between the two groups. VLSD was associated with a shorter operation time (P = 0.020) and less postoperative complications (P < 0.0001), including less diarrhea (P < 0.0001), epigastric fullness (P < 0.0001), and delayed gastric em...Continue Reading

References

Jan 1, 1981·American Journal of Surgery·M Ihasz, C A Griffith
Feb 1, 1996·The British Journal of Surgery·H IsozakiY Takeda
Jul 3, 2008·Surgical Endoscopy·Kazuyuki KojimaKenichi Sugihara
Jul 18, 2009·World Journal of Gastroenterology : WJG·Xiao-Zhong JiangYou-Jiang Tao
Jul 2, 2011·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Michael L HibbardLee L Swanström
Aug 23, 2012·World Journal of Gastroenterology : WJG·Hyung Hun KimWon Moon
Jan 30, 2013·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Cheng ZheZheng Shu-guo
Jun 28, 2013·Surgical Innovation·Guoqing JiangDousheng Bai
Jul 9, 2013·Journal of Smooth Muscle Research = Nihon Heikatsukin Gakkai Kikanshi·Haruaki MurakamiToshihiro Hirai
May 28, 2016·The Journal of Surgical Research·Mena M HannaDanny Yakoub

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Citations

May 7, 2021·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Xu LiRenyi Qin

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