Valid Exposure Protocols Needed in Magnetic Resonance Imaging Genotoxic Research

Bioelectromagnetics
Jonna WilénKjell Hansson Mild

Abstract

Several in vitro and in vivo studies have investigated if a magnetic resonance imaging (MRI) examination can cause DNA damage in human blood cells. However, the electromagnetic field (EMF) exposure that the cells received in the MR scanner was not sufficiently described. The first studies looking into this could be regarded as hypothesis-generating studies. However, for further exploration into the role of MRI exposure on DNA integrity, the exposure itself cannot be ignored. The lack of sufficient method descriptions makes the early experiments difficult, if not impossible, to repeat. The golden rule in all experimental work is that a study should be repeatable by someone with the right knowledge and equipment, and this is simply not the case with many of the recent studies on MRI and genotoxicity. Here we discuss what is lacking in previous studies, and how we think the next generation of in vitro and in vivo studies on MRI and genotoxicity should be performed. Bioelectromagnetics. © 2020 Bioelectromagnetics Society.

References

Dec 18, 2001·Journal of Magnetic Resonance Imaging : JMRI·W G SchreiberJ G Hengstler
Jun 20, 2002·IARC Monographs on the Evaluation of Carcinogenic Risks to Humans·UNKNOWN IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Mar 21, 2007·Magnetic Resonance Imaging·Alayar KangarluTamer S Ibrahim
Oct 31, 2007·Journal of Magnetic Resonance Imaging : JMRI·Nina F SchwenzerEnno Rodegerdts
Mar 12, 2009·Health Physics·UNKNOWN International Commission on Non-Ionizing Radiation Protection
Nov 12, 2010·Health Physics·UNKNOWN International Commission on Non-Ionizing Radiation Protection
Mar 18, 2011·Bioelectromagnetics·Joong Won LeeHai Won Chung
May 31, 2011·Clinical Biochemistry·Sema YildizMehmet A Eren
May 18, 2013·International Journal of Radiation Biology·Ágnes SzerencsiGyörgy Thuróczy
Jun 25, 2013·European Heart Journal·Michael FiechterPhilipp A Kaufmann
Jul 4, 2013·European Heart Journal·Juhani KnuutiHeikki Minn
Mar 1, 2013·Journal of Advanced Research·Haitham S MohammedAnwar A Elsayed
Jun 5, 2015·Mutation Research. Reviews in Mutation Research· VijayalaxmiOliver Speck
Sep 5, 2015·Circulation. Cardiovascular Imaging·Patrizio LancellottiCécile Oury
Jun 9, 2016·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Kelvin J LaytonMaxim Zaitsev
Aug 24, 2016·European Heart Journal Cardiovascular Imaging·M A HillW G McKenna
Jan 6, 2017·Radiation Research·Kenneth R FosterThomas F Budinger
Mar 8, 2017·European Journal of Radiology·Soo Jung Kim, Kyung Ah Kim
Nov 3, 2017·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Jon-Fredrik Nielsen, Douglas C Noll
Nov 23, 2017·European Heart Journal·William R CritchleyChristopher A Miller
Dec 28, 2017·European Heart Journal·Mark A Hill
Dec 1, 2018·Bioelectromagnetics·Jennifer FrankelJonna Wilén

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