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Validating maps from single particle electron cryomicroscopy

Current Opinion in Structural Biology

Nov 26, 2015

Peter B Rosenthal, John L Rubinstein

Abstract

Progress in single particle cryo-EM, most recently due to the introduction of direct detector devices, has made the high-resolution structure determination of biological assemblies smaller than 500kDa more routine, but has also increased attention on the need for tools to demonstrate th...read more

Mentioned in this Paper

Research
Crystallography, X-Ray
Evaluation
Electron Microscopy
Tilt (brand of fungicide)
Detector Device Component
Cryoelectron Microscopy
Reproducibility of Results
Particle
Validation
3
95
Paper Details
References
  • References56
  • Citations7
12345...
  • References56
  • Citations7
1

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Validating maps from single particle electron cryomicroscopy

Current Opinion in Structural Biology

Nov 26, 2015

Peter B Rosenthal, John L Rubinstein

PMID: 26605834

DOI: 10.1016/j.sbi.2015.07.002

Abstract

Progress in single particle cryo-EM, most recently due to the introduction of direct detector devices, has made the high-resolution structure determination of biological assemblies smaller than 500kDa more routine, but has also increased attention on the need for tools to demonstrate th...read more

Mentioned in this Paper

Research
Crystallography, X-Ray
Evaluation
Electron Microscopy
Tilt (brand of fungicide)
Detector Device Component
Cryoelectron Microscopy
Reproducibility of Results
Particle
Validation
3
95

Similar Papers Found In These Feeds

Cryogenic Electron Microscopy

Cryogenic electron microscopy (Cryo-EM) allows the determination of biological macromolecules and their assemblies at a near-atomic resolution. Here is the latest research.

Cryogenic Electron Microscopy (Keystone)

Cryogenic electron microscopy (Cryo-EM) uses a specific technique to allow for the visualization of macromolecules and their assemblies at a near-atomic resolution. Discover the latest research on Cryo-EM here.

Related Papers

Nature Methods

Prevention of overfitting in cryo-EM structure determination

Nature MethodsJuly 31, 2012
Sjors H W Scheres, Shaoxia Chen
Paper Details
References
  • References56
  • Citations7
12345...
  • References56
  • Citations7
1
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