Validating marker-based incidence estimates in repeatedly screened populations

Biometrics
G A SattenS Datta

Abstract

Disease incidence (new cases of disease per person per year) is usually measured by using longitudinal data. However, several recent proposals for measuring the incidence of human immunodeficiency virus (HIV) rely on cross-sectional data only. These methods assume each person is only sampled once; however, in some instances, it is necessary to consider these cross-sectional methods when individuals are represented more than once in the survey sample. We derive an extension of the cross-sectional incidence estimator that is valid for data from repeatedly screened populations and show under what conditions our new estimator reduces to the old estimator. An example involving estimation of HIV incidence among repeat blood donors is presented.

References

Apr 30, 1998·Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association·E H KaplanS Pollack
Jul 11, 1998·JAMA : the Journal of the American Medical Association·R S JanssenM P Busch

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Citations

Apr 27, 2005·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Timothy A KelloggWilli McFarland
Nov 21, 2009·The Lancet Infectious Diseases·Rebecca GuyUNKNOWN WHO Working Group on HIV Incidence Assays
May 17, 2008·Transfusion·Josiane PillonelUNKNOWN Transfusion-Transmissible Agents Working Group of the French Society of Blood Transfusion
Jun 12, 2008·Cadernos de saúde pública·Greice Maria Silva da Conceição, Maria Tereza Serrano Barbosa

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