Validating the Geriatric Depression Scale with proxy-based data: A case-control psychological autopsy study in rural China

Journal of Affective Disorders
Lu NiuLiang Zhou

Abstract

The Geriatric Depression Scale (GDS) has been widely used for late-life depression, but it lacks validation in psychological autopsy research. This study aimed to assess the validity and establish the optimal cut-off values of the GDS-30 and the GDS-15 with proxy-based data in rural China. We applied psychological autopsy to collect data from 242 consecutive suicide cases and 242 paired living community controls. Subject-proxy concordance for the GDS-30 (ICC = 0.590) and the GDS-15 (ICC = 0.539) were fair in the living controls. Based on proxy-data, we found that the suicide cases had higher scores of depression than the living controls did; the values of Cronbach's alpha demonstrated good internal consistency of the GDS-30 and the GDS-15; the Spearman correlation analysis indicated that the GDS scores were correlated with hopelessness, loneliness, and quality of life. For suicide cases, the GDS-30 showed the highest Youden's index as 34.86% with a cut-off value at 22, when its sensitivity and specificity was 0.78 and 0.56, respectively; the score of 12 on the GDS-15 showed the highest Youden's index of 31.39%, and its sensitivity and specificity was 0.74 and 0.58, respectively. This study is limited to its generalizability to ...Continue Reading

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Citations

May 11, 2020·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Wei ZhouShimin Zheng
Dec 6, 2019·The Journal of Nervous and Mental Disease·Yan-Xin WeiCun-Xian Jia
Mar 14, 2021·Journal of Psychiatric Research·Modhurima MoitraAlize Ferrari
Mar 18, 2021·The Australian and New Zealand Journal of Psychiatry·Guojun WangLiang Zhou
Jul 20, 2021·Work : a Journal of Prevention, Assessment, and Rehabilitation·Minshu GeHallie Lee
Sep 26, 2021·Environmental Science and Pollution Research International·Wenjia PengYing Wang

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