Validation and analysis of dose distributions in a new and entirely redesigned cobalt-60 stereotactic radiosurgery units

Nihon Hoshasen Gijutsu Gakkai zasshi
Hisato NakazawaMasataka Komori

Abstract

The objective of this study was to evaluate the reproducibility of dose distributions in stereotactic treatment planning throughout Gamma Knife (GK) stereotactic radiosurgery (SRS) procedures in both GK model C and Perfexion (PFX). An originally-developed phantom and a radiochromic film were used for obtaining actual dose distributions. The phantom, with inserted films, was placed on a Leksell skull frame. Computed tomography (CT) was then acquired with a stereotactic localizer box attached to the frame, dose planning was made using the Leksell GammaPlan treatment planning system, and the phantom was ended up as beam delivery on an equal with clinical radiosurgery process. The reproducibility of the dose plan was provided by distance to agreement (DTA) values between planned and irradiated dose distributions calculated by dedicated film analysis software. The DTA values were determined for the isodose lines at 30%, 50%, 70%, and 90% of the maximum dose. In our study, the reproducibility of dose distributions in GK PFX was lower than in GK model C. As the results common to both units, the mean values of middle dose area (50% isodose) were about half the values of high (90% isodose) and low (30% isodose) dose area. Therefore vali...Continue Reading

References

May 30, 2007·Journal of Applied Clinical Medical Physics·Panagiotis SandilosAngelos Angelopoulos
Oct 3, 2007·Neurosurgery·Christer Lindquist, Ian Paddick
Oct 14, 2011·Medical Physics·Jeong-Hoon ParkHyun-Tai Chung

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