Validation of a computerised measurement system for guided routine evaluation of cardiovascular autonomic neuropathy

Computer Methods and Programs in Biomedicine
G VespasianiM M Benedetti

Abstract

A study for evaluating the use of the Cardionomic system was conducted in six Italian Centres for Diabetes. Cardionomic is a portable computerised system that is used for a guided step-by-step performance of several cardiovascular tests for autonomic neuropathy (heart rate and blood pressure). It has been compared to the traditional method using an electrocardiograph. In this study, which involved 74 diabetic patients, 392 cardiovascular tests were conducted with the electrocardiograph and 392 were done using the portable system. The results were compared to the results obtained with the ECG assuming the latter as the standard ones. All the indices of validity that were investigated (sensitivity, specificity, positive predictive value, negative predictive value, positive likelihood ratio, negative likelihood ratio) indicate that the proposed system is reliable. Because it saves a considerable amount of time and is also easy to use, it represents a valid alternative for the routine screening of autonomic neuropathy.

References

Apr 12, 1990·The New England Journal of Medicine·W R KennedyJ S Najarian
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Citations

Feb 29, 2008·BMC Gastroenterology·Agostino Di CiaulaPiero Portincasa
Jul 3, 2009·Diabetes & Metabolism·J Cabezas-CerratoUNKNOWN neuropathy Spanish study group of the Spanish Diabetes Society (SDS)
Apr 17, 2008·Journal of Diabetes and Its Complications·Andrea ViggianoBruno De Luca
Jul 15, 2006·Metabolism: Clinical and Experimental·Iacopo ChiodiniGuido Adda
Jul 31, 2013·International Journal of Cardiology·Zi-Hui TangLinuo Zhou
Apr 5, 2012·Experimental Diabetes Research·G GarrutiF Giorgino
Apr 21, 2016·PloS One·Zannatul FerdousFrank Christopher Howarth
Aug 22, 2016·Revista clínica española·T Lozano, J Ena

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