Validation of a Deep Learning Model to Screen for Glaucoma Using Images from Different Fundus Cameras and Data Augmentation.

Ophthalmology. Glaucoma
Ryo AsaokaYoshiaki Kiuchi

Abstract

To validate a deep residual learning algorithm to diagnose glaucoma from fundus photography using different fundus cameras at different institutes. Cross-sectional study. A training dataset consisted of 1364 color fundus photographs with glaucomatous indications and 1768 color fundus photographs without glaucomatous features. Two testing datasets consisted of (1) 95 images of 95 glaucomatous eyes and 110 images of 110 normative eyes, and (2) 93 images of 93 glaucomatous eyes and 78 images of 78 normative eyes. A deep learning algorithm known as Residual Network (ResNet) was used to diagnose glaucoma using a training dataset. The 2 testing datasets were obtained using different fundus cameras (different manufacturers) across multiple institutes. The size of the training data was artificially increased by adding minor alterations to the original data, known as "image augmentation." Diagnostic accuracy was assessed using the area under the receiver operating characteristic curve (AROC). Area under the receiver operating characteristic curve. When image augmentation was not used, the AROC was 94.8% (90.3-96.8) in the first testing dataset and 99.7% (99.4-100.0) in the second dataset. These AROC values were significantly (P < 0.05) ...Continue Reading

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Citations

Aug 21, 2020·Translational Vision Science & Technology·Mark ChristopherLinda M Zangwill
Sep 4, 2020·Translational Vision Science & Technology·Olivia E O'LearyDavid Goldblum
Aug 25, 2020·Translational Vision Science & Technology·Adrian GaldranHadi Chakor
Dec 5, 2020·European Journal of Ophthalmology·Delaram MirzaniaKelly W Muir
Apr 25, 2021·Mathematical Biosciences and Engineering : MBE·Amsa ShabbirTehmina Shehryar
Jul 16, 2021·The British Journal of Ophthalmology·Kenichi NakaharaHiroshi Murata
Oct 17, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Saki NomaTaiji Sakamoto
Aug 28, 2021·Journal of Clinical Medicine·Sze H Wong, James C Tsai
Sep 16, 2021·Translational Vision Science & Technology·Vincent YuenCarol Y Cheung

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