Validation of a novel ultrasound dilution method to measure cardiac output during hemodialysis

ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs
V V Kisloukhine, D A Dean

Abstract

A method to measure cardiac output (CO) based on ultrasound velocity dilution during hemodialysis was validated in an animal model against direct measurement using a transit time technique and a calibrated pump. In two anesthetized pigs, a 20 mm transit time ultrasound flow probe was placed on the ascending aorta to measure CO, and the right femoral artery and vein were cannulated for hemodialysis access. The dual sensor HD01 Hemodialysis Monitor was positioned on the arterial and venous tubing lines for measurement of cardiac output by ultrasound velocity dilution (COUD) by intravenous injections of 10-20 ml isotonic saline at 37 degrees C. COUD (n = 29) was compared with CO from the transit time flow probe (COT). During the second part of the experiment, the animal was placed on right atrial to left atrial bypass using a calibrated roller pump. The COUD (n = 9) was compared with cardiac output as measured by pump flow (COP). A linear relationship was observed between COUD and COT (COUD) = 0.948 x COT + 0.086 L/min, r = 0.95), and between COUD and COP (COUD = 1.06 x COP-0.327 L/min, r = 0.99). Thus, cardiac output measured by ultrasound velocity dilution during hemodialysis is in good agreement with well established, but invas...Continue Reading

Citations

May 23, 2008·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Nikolai M KrivitskiNaveen V Thuramalla
Jun 3, 1999·Clinical Chemistry and Laboratory Medicine : CCLM·B Stegmayr
Sep 4, 2015·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Philip Andreas SchytzHenrik Post Hansen
Sep 1, 2005·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Nikolaos KaramperisJens Dam Jensen
Jan 11, 2018·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Clare MacEwenLionel Tarassenko
Jan 20, 2011·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Alexsandr A Eremenko, Perviz N Safarov
Sep 22, 2007·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Thomas M KitzlerNathan W Levin
Mar 29, 2018·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Stefanie HaagFerruh Artunc

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