Validation of a Sequential Organ Failure Assessment Score using Electronic Health Record Data

Journal of Medical Systems
Luis E HuertaSMART Investigators and the Pragmatic Critical Care Research Group

Abstract

The sequential organ failure assessment (SOFA) score is a scoring system commonly used in critical care to assess severity of illness. Automated calculation of the SOFA score using existing electronic health record data would broaden its applicability. We performed a manual validation of an automated SOFA score previously developed at our institution. A retrospective analysis of a random subset of 300 patients from a previously published randomized trial of critically ill adults was performed, with manual validation of SOFA scores from the date of initial intensive care unit admission. Spearman's rank correlation coefficient, weighted Cohen's kappa, and Bland-Altman plots were used to assess agreement between manual and electronic versions of SOFA scores and between manual and electronic versions of their individual components. There was high agreement between manual and electronic SOFA scores (Spearman's rank correlation coefficient = 0.90, 95% CI 0.87-0.93). Renal and respiratory components had lower agreement (weighted Cohen's kappa = 0.63, 95% CI 0.53-0.73 for renal; weighted Cohen's kappa = 0.77, 95% CI 0.70-0.84 for respiratory). The area under the receiver operating characteristic curve (AUC) for 30-day in-hospital morta...Continue Reading

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Citations

Feb 1, 2020·Annals of the American Thoracic Society·Christina S BoncykRobert E Freundlich
Jul 20, 2019·Turkish Journal of Emergency Medicine·Rodrigo de Freitas GarberoVinícius Gabriel Monteiro von Zuben
Feb 25, 2020·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Michaël SauthierPhilippe Jouvet
Mar 21, 2020·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Emily L JoyceJohn A Kellum
Aug 28, 2020·Resuscitation·Andrew BairdUNKNOWN University of Pittsburgh Post-Cardiac Arrest Service
Mar 17, 2021·Neurocritical Care·Jennifer A FronteraSteven Galetta
Sep 4, 2021·Journal of Tropical Pediatrics·Dibyendu RaychaudhuriRakesh Mondal

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