Validation of an ultrasound dilution technology for cardiac output measurement and shunt detection in infants and children

Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
Lars LindbergValeria Perez-de-Sa

Abstract

To validate cardiac output measurements by ultrasound dilution technology (COstatus monitor) against those obtained by a transit-time ultrasound technology with a perivascular flow probe and to investigate ultrasound dilution ability to estimate pulmonary to systemic blood flow ratio in children. Prospective observational clinical trial. Pediatric cardiac operating theater in a university hospital. In 21 children (6.1 ± 2.6 kg, mean ± SD) undergoing heart surgery, cardiac output was simultaneously recorded by ultrasound dilution (extracorporeal arteriovenous loop connected to existing arterial and central venous catheters) and a transit-time ultrasound probe applied to the ascending aorta, and when possible, the main pulmonary artery. The pulmonary to systemic blood flow ratio estimated from ultrasound dilution curve analysis was compared with that estimated from transit-time ultrasound technology. Bland-Altman analysis of the whole cohort (90 pairs, before and after surgery) showed a bias between transit-time ultrasound (1.01 ± 0.47 L/min) and ultrasound dilution technology (1.03 ± 0.51 L/min) of -0.02 L/min, limits of agreement -0.3 to 0.3 L/min, and percentage error of 31%. In children with no residual shunts, the bias was -...Continue Reading

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Citations

Sep 1, 2015·Journal of Clinical Monitoring and Computing·Koichi SuehiroMaxime Cannesson
Sep 23, 2014·Journal of Clinical Monitoring and Computing·R SaxenaS M Tibby
Aug 3, 2017·Journal of Feline Medicine and Surgery·Manuel Martin-FloresLuis Campoy
Jan 11, 2018·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Clare MacEwenLionel Tarassenko
Mar 26, 2019·Anesthesiology·Theodor S SigurdssonLars Lindberg
Apr 21, 2018·Frontiers in Pediatrics·Sabine L VranckenWillem P de Boode
Jan 30, 2020·Scientific Reports·Theodor Skuli Sigurdsson, Lars Lindberg
Oct 6, 2020·Acta Anaesthesiologica Scandinavica·Theodor S Sigurdsson, Lars Lindberg

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