Validation of collateral scoring on flat-detector multiphase CT angiography in patients with acute ischemic stroke

PloS One
Ilko L MaierDavid S Liebeskind

Abstract

The pivotal impact of collateral circulation on outcomes in endovascular therapy has fueled the development of numerous CTA collateral scales, yet synchronized validation with conventional angiography has never occurred. We validated multiphase flat-detector CTA (mpFDCTA) for collateral imaging in patients undergoing endovascular stroke treatment. Consecutive acute ischemic stroke patient data, including mpFDCTA shortly followed by digital subtraction angiography (DSA), in the setting of acute ICA- or MCA-occlusions were analyzed. An independent core lab scored mpFDCTA with an established collateral scale and separately graded American Society of Interventional and Therapeutic Neuroradiology (ASITN) collateral score on DSA, blind to all other data. 24 consecutive cases (age 76.7 ± 7.3 years; 58.3% women; baseline NIHSS median 17 (4-23)) of acute ICA- or MCA-occlusion were analyzed. Time from mpFDCTA to intracranial DSA was 23.04 ± 7.6 minutes. Median mpFDCTA collateral score was 3 (0-5) and median DSA ASITN collateral score was 2 (0-3), including the full range of potential collateral grades. mpFDCTA and ASITN collateral score were strongly correlated (r = 0.86, p<0.001). mpFDCTA provided more complete collateral data compared ...Continue Reading

References

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Citations

Jul 29, 2019·Current Neurology and Neuroscience Reports·R WannamakerK Butcher
Dec 15, 2019·Journal of Clinical Medicine·Marios-Nikos PsychogiosJan Liman
Oct 6, 2018·Neuroradiology·Daniel-Alexandre BissonRichard I Aviv

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Methods Mentioned

BETA
sedation
imaging technique

Software Mentioned

mpFDCTA
MedCalc
Syngo X

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