Validation of diabetic retinopathy and maculopathy diagnoses recorded in a U.K. primary care database.

Diabetes Care
Elisa Martín-MerinoLuis Alberto García-Rodríguez

Abstract

To describe the validity of recorded diabetic retinopathy (DR) and diabetic maculopathy (DMP) diagnoses, including edema (DMO) in The Health Improvement Network (THIN) database. In two independent computer searches, we detected 20,838 patients with diabetes aged 1-84 years with a first DR computer Read entry in 2000-2008 and 4,064 with a first DMP entry. A two-step strategy was used to validate both outcomes as follows: 1) review of patient profiles including free-text comments from primary care practitioners (PCPs) (containing referral information and test results) of a random sample of 500 DR and all DMP computer-detected patients. We classified them in probable, possible, and noncase according to the diagnosis plausibility based on the manual review of the computerized information; and 2) review of questionnaires sent by PCPs and medical records in a random sample (N = 200 for each outcome including 36 diabetic macular edema [DMO]). Gold standard was PCPs' confirmation. After profiles review, we categorized 418 as probable/possible DR. In addition, 3,676 DMP were categorized as probable/possible (including 711 DMO). After review of information sent by PCPs, confirmation rates were 87.3 and 87.2%, respectively (90.3% for DMO)...Continue Reading

References

Aug 20, 2003·Diabetic Medicine : a Journal of the British Diabetic Association·N YounisJ P Vora
Oct 15, 2003·Archives of Ophthalmology·Frank A SloanPaul P Lee
Dec 21, 2004·Informatics in Primary Care·Alison BourkeMichael Robinson
Oct 27, 2006·Pharmacoepidemiology and Drug Safety·James D LewisBrian L Strom
Jul 16, 2008·Archives of Ophthalmology·Srilaxmi BearellyPaul P Lee
Feb 26, 2009·Journal of Epidemiology and Community Health·E L Massó GonzálezL A García Rodríguez
Jun 23, 2009·Primary Care Diabetes·Sreedhar JyothiSobha Sivaprasad
Jul 23, 2009·Pharmacoepidemiology and Drug Safety·Andrea V MargulisSonia Hernández-Díaz
Feb 5, 2010·Pharmacoepidemiology and Drug Safety·Ana RuigómezLuis Alberto García Rodríguez
Aug 3, 2010·QJM : Monthly Journal of the Association of Physicians·W GunathilakeI Idris
Sep 14, 2010·Diabetes Care·Antonio Gonzalez-PerezLuis A García Rodríguez
Sep 22, 2010·Diabetic Medicine : a Journal of the British Diabetic Association·J GenzA Icks
Oct 27, 2010·BMJ : British Medical Journal·Zoe Ockrim, David Yorston

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Citations

Jul 3, 2013·Diabetologia·S Asghari, M Mahdavian
Jun 26, 2014·PloS One·Elisa Martín-MerinoLuis Alberto García-Rodríguez
Nov 16, 2013·The European Journal of Contraception & Reproductive Health Care : the Official Journal of the European Society of Contraception·Lucía Cea SorianoLuis A García-Rodríguez
Feb 11, 2016·Primary Care Diabetes·Elisa Martín-MerinoLuis Alberto Garcia-Rodriguez
Jan 1, 2014·Pharmacoepidemiology and Drug Safety·Ronac MamtaniJames D Lewis
Oct 6, 2015·Pharmacoepidemiology and Drug Safety·Lucía Cea SorianoLuis A García Rodríguez
Mar 11, 2017·Diabetes Therapy : Research, Treatment and Education of Diabetes and Related Disorders·Michael FeherDaniel R Witte
Oct 4, 2020·Pharmacoepidemiology and Drug Safety·Ana RuigómezLuis A García Rodríguez
Jul 3, 2021·Healthcare·Elitsa HristovaKlara Dokova

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