Validation of injection parameters for catheter-directed intraarterial gadolinium-enhanced MR angiography

Academic Radiology
Reed A OmaryT M Grist

Abstract

Catheter-directed intraarterial (IA) injections of gadolinium contrast agents may be used during endovascular interventions with magnetic resonance (MR) imaging guidance. Injection protocols require further validation. Using a flow phantom and swine, the authors aimed to (a) measure the optimal arterial gadolinium concentration ([Gd]) required for MR angiography and (b) validate a proposed IA injection protocol for gadolinium-enhanced MR angiography. For in vitro experiments, the authors placed a catheter in the aorta of an aorto-renal-iliac flow phantom. Injected [Gd], injection rates, and aortic blood flow rates were varied independently for 36 separate IA gadolinium injections. The authors performed 2D and 3D MR angiography with a fast spoiled gradient-recalled echo sequence. For subsequent in vivo experiments, they selectively placed catheters within the aorta, renal artery, or common iliac artery of three pigs. Injection rate and injected [Gd] were varied. The authors performed 32 separate IA gadolinium injections for 2D MR angiography. Signal-to-noise ratios (SNRs) were compared for the various combinations of injection rate and injected [Gd]. In vitro, an arterial [Gd] of 2%-4% produced an optimal SNR for 2D MR angiograp...Continue Reading

References

Sep 1, 1996·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·F R KorosecC A Mistretta
Sep 4, 1998·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·O UnalC A Mistretta
Dec 10, 1999·Journal of Vascular and Interventional Radiology : JVIR·R A OmaryC M Strother
Mar 29, 2000·Journal of Vascular and Interventional Radiology : JVIR·R A OmaryT M Grist
Sep 21, 2000·Journal of Vascular and Interventional Radiology : JVIR·R A OmaryT M Grist
Sep 30, 2000·Radiology·J M SerfatyX Yang
Oct 12, 2000·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·C BosM A Viergever
Dec 1, 2000·Journal of Vascular and Interventional Radiology : JVIR·R FrayneC M Strother

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Citations

Apr 29, 2005·The International Journal of Cardiovascular Imaging·Kostaki G BisWilliam O'Neill
Apr 25, 2012·AJR. American Journal of Roentgenology·Ron C GabaReed A Omary
Jul 24, 2003·AJR. American Journal of Roentgenology·Frank K WackerJonathan S Lewin
Feb 17, 2005·Journal of Vascular and Interventional Radiology : JVIR·Reed A OmaryDebiao Li
Aug 13, 2002·Radiologic Clinics of North America·Reed A OmaryDebiao Li
Jun 2, 2004·Journal of Magnetic Resonance Imaging : JMRI·Nikolaos V TsekosPamela K Woodard
Mar 9, 2007·Journal of Magnetic Resonance Imaging : JMRI·C HashagenDeniz Bilecen

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