Validation of modified early warning score using serum lactate level in community-acquired pneumonia patients. The National Early Warning Score-Lactate score

The American Journal of Emergency Medicine
Sion JoBoyoung Park

Abstract

The aim of this study was to investigate the prognostic prediction power of a newly introduced early warning score modified by serum lactate level, the National Early Warning Score-Lactate (NEWS-L) score, among community-acquired pneumonia (CAP) patients. We also compared the NEWS-L score with the pneumonia severity index (PSI) and CURB-65. We designed a retrospective observational study and collected data on confirmed adult CAP patients who visited the study hospital between October 2013 and September 2014. Variables relevant to, the NEWS-L score, PSI, and CURB-65 were extracted from electronic medical records. Survival status at hospital discharge was determined in the same manner. The NEWS-L score was calculated as NEWS-L=NEWS+serum lactate level (mmol/L). The NEWS-L was divided into quartiles. The ability to predict mortality was assessed through area under the receiver operating characteristic curve analysis and calibration analysis. A total of 553 patients were enrolled, and the inpatient mortality rate was 10.8% (n=60). Mortality rates increased incrementally in conjunction with the NEWS-L quartiles: first quartile, 2.2%; second quartile, 7.9%; third quartile, 9.6%; and fourth quartile, 23.9%. The area under the receiver...Continue Reading

References

Mar 1, 1996·Annals of Emergency Medicine·E H GilbertJ Steiner
Jul 1, 1996·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·J G YoungerS G Rothrock
Jan 23, 1997·The New England Journal of Medicine·M J FineW N Kapoor
Apr 1, 1997·Annals of Emergency Medicine·E J GallagherM Touger
Sep 16, 1998·Clinical Therapeutics·M S NiedermanR Popovian
Jan 18, 2006·American Journal of Epidemiology·Neil J Perkins, Enrique F Schisterman
Feb 6, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Lionel A MandellUNKNOWN American Thoracic Society
Oct 14, 2009·Thorax·W S LimUNKNOWN Pneumonia Guidelines Committee of the BTS Standards of Care Committee
Mar 6, 2010·Postgraduate Medicine·Thomas M File, Thomas J Marrie
Jul 20, 2010·Resuscitation·David R PrytherchPeter I Featherstone
May 1, 2013·European Journal of Emergency Medicine : Official Journal of the European Society for Emergency Medicine·Sion JoBoyoung Park
Nov 15, 2013·BioMed Research International·Chun Shing KwokPhyo Kyaw Myint
Mar 18, 2015·The New England Journal of Medicine·Paul R MounceyUNKNOWN ProMISe Trial Investigators
Mar 21, 2015·The American Journal of Emergency Medicine·Min Hyuk GwakBoyoung Park
Sep 30, 2014·Clinical and Experimental Emergency Medicine·Jean-Louis VincentDaniel De Backer

❮ Previous
Next ❯

Citations

Sep 24, 2013·Journal of Perianesthesia Nursing : Official Journal of the American Society of PeriAnesthesia Nurses·Barbara Godden
Apr 14, 2017·Journal of the American Geriatrics Society·Emanuela CataudellaLorenzo Malatino
Dec 31, 2019·Journal of Clinical Nursing·Martin SpångforsKarin Samuelson
Jun 20, 2020·BMC Medical Informatics and Decision Making·Andrew Hao Sen FangTharmmambal Balakrishnan
Jan 1, 2021·The Indian Journal of Medical Research·Aynur Ecevit KayaEngin Deniz Arslan

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.