Validation of recommended definition in identifying elevated blood pressure in adolescents

The Journal of Clinical Hypertension
Hui FanXingyu Zhang

Abstract

Recently, the American Academy of Pediatrics (AAP) recommended 120/80 mm Hg as thresholds for identifying elevated blood pressure (BP) in adolescents aged 13-17 years. The authors aimed to compare the performance of the new definition in identifying elevated BP with traditional percentile-based definition. Data were obtained from the National Health and Nutrition Examination Survey 1999-2014, which included 7485 adolescents aged 13-17 years. Elevated BP was defined using the recommended (≥120/80 mm Hg) and traditional definition (≥90th percentile for sex, age, and height or 120/80 mm Hg) presented in AAP guideline. The prevalence of elevated BP was 15.7% and 17.2% using the recommended and traditional definition, respectively (P < .001). The recommended definition had high sensitivity (90.9%), perfect specificity (100.0%), perfect positive predictive value (100.0%), and very high negative predictive value (98.1%) compared with the traditional definition. The Kappa correlation coefficient between two definitions was 0.94 (P < .001). Similar results can be observed in subgroups across sex, age, and sex- and age-specific height percentile except for both sexes with young age and low height percentile. Generally, our results suppor...Continue Reading

References

Aug 3, 2004·Pediatrics·UNKNOWN National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents
Jan 18, 2005·Lancet·Patricia M KearneyJiang He
Aug 23, 2007·JAMA : the Journal of the American Medical Association·Matthew L HansenDavid C Kaelber
Jan 31, 2008·American Journal of Epidemiology·B RosnerB Falkner
Nov 16, 2011·Pediatrics·UNKNOWN Expert Panel on Integrated Guidelines for Cardiovascular Health and Risk Reduction in Children and Adolescents, UNKNOWN National Heart, Lung, and Blood Institute
May 21, 2014·The Lancet. Diabetes & Endocrinology·UNKNOWN Global Burden of Metabolic Risk Factors for Chronic Diseases Collaboration
Dec 6, 2014·Jornal de pediatria·Felipe Alves MouratoSandra da Silva Mattos
Jul 3, 2015·Clinical Pediatrics·Chunming MaQiang Lu
Mar 30, 2016·Hypertension·Bonita Falkner, Samuel S Gidding
Dec 13, 2016·Pediatrics·David C KaelberUNKNOWN Comparative Effectiveness Research Through Collaborative Electronic Reporting (CER2) Consortium
Aug 23, 2017·Pediatrics·Joseph T FlynnUNKNOWN SUBCOMMITTEE ON SCREENING AND MANAGEMENT OF HIGH BLOOD PRESSURE IN CHILDREN

❮ Previous
Next ❯

Citations

Aug 6, 2019·The Journal of Clinical Hypertension·Adina Mihaela Epure, Arnaud Chiolero

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.