Validation of Reported Whole-Grain Intake from a Web-Based Dietary Record against Plasma Alkylresorcinol Concentrations in 8- to 11-Year-Olds Participating in a Randomized Controlled Trial

The Journal of Nutrition
Anja Biltoft-JensenRikard Landberg

Abstract

Whole-grain (WG) intake is important for human health, but accurate intake estimation is challenging. Use of a biomarker for WG intake provides a possible way to validate dietary assessment methods. Our aim was to validate WG intake from 2 diets reported by children, using plasma alkylresorcinol (AR) concentrations, and to investigate the 3-mo reproducibility of AR concentrations and reported WG intake. AR concentrations were analyzed in fasting blood plasma samples, and WG intake was estimated in a 7-d web-based diary by 750 participants aged 8-11 y in a 2 school meal × 3 mo crossover trial. Reported WG intake and plasma AR concentrations were compared when children ate their usual bread-based lunch (UBL) and when served a hot lunch meal (HLM). Correlations and cross-classification were used to rank subjects according to intake. The intraclass correlation coefficients (ICCs) between subjects' measurements at baseline and after the UBL were used to assess reproducibility. Correlations between reported WG wheat + rye intake and plasma AR were 0.40 and 0.37 (P < 0.001) for the UBL and the HLM diets, and 78% and 77% were classified in the same or adjacent quartiles for the UBL and HLM diets, respectively. The ICC over 3 mo was 0.4...Continue Reading

Associated Clinical Trials

Oct 24, 2011·Arne Astrup

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Citations

Nov 8, 2016·Molecular Metabolism·Yan Y Lam, Eric Ravussin
Jun 26, 2018·Current Opinion in Clinical Nutrition and Metabolic Care·Johanna ConradUte Nöthlings
Oct 8, 2019·Journal of Medical Internet Research·Anna Karin LindroosEva Warensjö Lemming
Apr 17, 2020·Rapid Communications in Mass Spectrometry : RCM·Jose Rodríguez-MoratóNirupa R Matthan

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