Validation of scalp coverage scoring methods for scalp hair loss in male pattern hair loss (androgenetic alopecia)

Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)
D Van NesteT Leroy

Abstract

Global evaluation of hair loss in male subjects affected by androgenetic alopecia has been proposed as a means for monitoring changes over time, including placebo-controlled drug efficacy studies. Because of the potential impact of subjectivity (e.g. placebo effect) of clinical investigators, global photographs (GPs) have been introduced as a more objective record. Examination of paired before and after pictures and rating on a seven-point scale (from greatly decreased -3 to greatly increased +3) have been historically introduced by United States of America (US) experts. Based on published GPs and original GPs obtained at our clinical research facility, we developed a training set in order to allow European Union (EU) observers to practice and compare with ratings by the US experts. After training with the seven-point scale, there was a positive correlation between three US and three EU ratings (n=52 paired images from 35 different subjects, r=0.795). The results of a test-retest evaluation was performed on 18 paired images from the initial image collection by the three EU experts. Correlation r=0.806 and identical scores in 78% of cases documents a reproducibility similar to the single one US expert published data (119 subject...Continue Reading

References

Oct 1, 1996·Dermatologic Clinics·D Canfield
Oct 20, 1998·Journal of the American Academy of Dermatology·K D KaufmanG J Gormley
Nov 9, 2000·The British Journal of Dermatology·D Van NesteK D Kaufman
Jan 22, 2003·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Dominique Van NesteEmmanuelle Sandraps
Feb 13, 2003·Journal of the American Academy of Dermatology·Elise A Olsen

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Citations

Sep 10, 1998·International Journal of Dermatology·D A Whiting
Jun 18, 2019·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Dominique Van Neste
May 26, 2006·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Petra Clara ArckEva Milena Johanne Peters
Nov 9, 2010·Dermatologic Therapy·Vincenzo De GiorgiTorello Lotti

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Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)
D Van NesteE Sandraps
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